Doppler Measurement of Uterine Artery
Conditions
Brief summary
The aim of this study is to investigate the inter- and intra-observer variability of first-trimester Uterine Artery Doppler ultrasound measurements in pregnancies between 11+0 and 13+0 weeks of gestation. Participants will undergo a measurement protocol (six sets of Doppler ultrasounds measurements of right and left uterine artery) performed alternately by two observers (sonographers or physicians who perform these ultrasounds frequently in clinical practice at the outpatient clinic).
Detailed description
Doppler ultrasound measurements are increasingly performed in clinical practice to detect high-risk pregnancies. First-trimester uterine artery Doppler measurement might be a potential predictor for the development of maternal hypertensive disorders later on in pregnancy. However, before implementing this measurement into clinical practice and prediction models, the test characteristics of this first-trimester Doppler measurements should be adequately studied. The objective is to assess the inter- and intra-observer variability of first-trimester uterine Doppler ultrasound measurements.
Interventions
DIAGNOSTIC_TESTDoppler ultrasound measurement
Doppler sonographic assessment of the uterine artery was performed transabdominally. Patients underwent six sets of Doppler ultrasounds measurements of both right and left uterine artery.
Sponsors
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Singleton pregnancy * Gestational age from 11+0 weeks to 13+6 weeks
Exclusion criteria
* Maternal age \<18 years * Inability to give informed consent * Multiple pregnancy * Abnormal fetal heart tracings * Non-viable pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Inter- and intra-observer variability of first-trimester Uterine artery Doppler ultrasound | Between 11 and 13 weeks of gestation. Measurements will take place during general appointments and will take an extra 2-3 minutes | The aim of this study is to investigate the inter- and intra-observer variability of first-trimester Uterine Artery Doppler ultrasound measurements, according to the TRUST-study criteria for reproducibility assessment and analysis. |
Countries
Netherlands
Outcome results
None listed