Liver Transplant
Conditions
Keywords
Liver transplant, Liver transplantation, Prehabilitation
Brief summary
This is a study developing a prehabilitation intervention and then testing the acceptability and feasibility of the intervention. Start date Aug 2022 for Focus groups and Feb 2023 Co-design workshops and feasibility study date pending
Detailed description
This study is using focus groups and experience based co-design workshops to co-design a remote multicomponent prehabilitation intervention for patients awaiting liver transplantation. Once the intervention is developed it will then be tested for acceptability and feasibility with the liver transplantation cohort in Belfast Northern Ireland.
Interventions
BEHAVIORALPrehabilitation
Remote prehabilitation multi-component.
Sponsors
Queen's University, Belfast
Belfast Health and Social Care Trust
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Intervention model description
Focus groups, experience based co-design and a feasibility study
Eligibility
Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* on the transplant waiting list * grade 3 below for encephalopathy
Exclusion criteria
* grade 4 above encephalopathy * Known adverse reaction to exercise * New stroke * lacks capacity to consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Recruitment | 6 months | It will be presented in percentage form and will be defined by 1. Number of participants active on the list. 2. Number of participants eligible to participate. 3. Number of participants informed about the iPRehab study. 4. Number of participants who were interested in participating. 5. Number of participants recruited. 6. Number of participants interested but didn't recruit and reasons why. 7. Number of participants who own a computer/phone/tablet. 8. Number of participants who can use a computer/phone/tablet independently. 9. Number of participants who need support to use a device. Detail the support required. Min score 0% Max Score 100% Higher values indicate a higher recruitment rate. |
| Adherence | 6 months | This will be recorded using percentage and will be defined by 1. Number of participants who attended 1:1 sessions. 2. Number of participants who attended the group exercise classes using a class log. 3. Number of participants who attend the online monthly peer support sessions while active on the liver transplantation waiting list. 4. Number of participants who accessed the website/web app. 5. Which sections of the website/web app are utilised and the number of participants who access each section. 6. Number of participants who wear the activity tracker and report weekly step count. Min score 0% Max Score 100% Higher values indicate a higher adherence rate. |
| Retention | 6 months | This will be recorded using percentage and will be defined by 1. Number of participants who completed the baseline assessment. 2. Number of participants who completed the 12-week iPRehab study. 3. Number of participants who completed the assessment 1 week post the iPRehab study. 4. Number of participants who completed the assessment 12 weeks post the iPRehab study. 5. Number of participants who drop out and the reasons Min score 0% Max Score 100% Higher values indicate a higher retention rate. |
| Acceptability | 6 months | This will be measured using an acceptability questionnaire. Min score 0% Max Score 100% Higher values indicate a higher acceptability. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Physical function | 6 months | 6 minute walk test. This will be recorded in meters covered in the 6 minute duration of the test. Min score 0 Max Score 1000 Higher values indicate better physical function. |
| Frailty | 6 months | The Liver frailty index. This index will determine the degree of frailty patients present while awaiting liver transplantation. This scale determines if the patients are frail, pre-frail or robust. Min score 1 Max Score 7 Higher values indicate a higher degree of frailty. |
Countries
United Kingdom
Contacts
Primary ContactSuzanne Lester, PhD
Backup ContactJudy Bradly, Prof
Outcome results
None listed