Airway Clearance Impairment
Conditions
Keywords
Airway clearance technique, Ventilator associated pneumonia, Electrical impedance tomography, High frequency chest wall oscillation, Chest physiotherapy
Brief summary
The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia. The main questions it aim to answer are: * effect of the therapies on volume changes * outcome on sputum clearance Participants will receive airway clearance techniques of * chest physiotherapy * high frequency chest wall oscillation.
Detailed description
Sputum can be accumulated in the airways of intubated patients, resulting in recurrent pneumonia. The airway clearance therapy is often utilized with chest physiotherapy or high frequency chest wall oscillation which has become popular for its easy of use and less time consuming to the healthcare workers. The main questions it aim to answer are on effectiveness of the therapies on lung volume changes and sputum clearance by two airway clearance techniques. With the oscillation of entire chest wall, the investigators hypothesize that the high frequency chest wall oscillation is more effectively clear sputum in the distal airways.
Interventions
Patients receive airway clearance by high frequency chest wall oscillation for 30 minutes twice a day.
PROCEDUREChest physiotherapy
Participants received chest physiotherapy twice a day
Sponsors
Hui-Ling Lin
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Masking description
The group will be coded and masked to the investigator and the outcome accessor.
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosed with chronic pulmonary disease * Diagnosed with ventilator associated pneumonia * Receive airway clearance therapy
Exclusion criteria
* Head injury, spinal injury * Instable hemodynamics * Intercranial pressure \> 20 cmH2O * Active hemoptysis * Empyema * Eye surgery * Abdominal distension * Chest tube insertion * Active tuberculosis
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| end-expiratory lung impedance | Measurement before intervention, 30 after, 1 hour and 2 hours after intervention | Changes of global of impedance of lungs measure by the electrical impedance tomography |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Weight of secretions | Sputum is collected before intervention, 30 after, 1 hour and 2 hours after intervention | Sputum amount is weighted. |
Countries
Taiwan
Outcome results
None listed