Pulmonaryhypertension in Copd at Different Levels of Smoking

Clinical Characteristics and Predictors of Pulmonary Hypertension in COPD at Different Levels of Smoking

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06031311

Enrollment

138

Registered

2023-09-11

Start date

2023-10-01

Completion date

2024-12-01

Last updated

2023-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pulmonary Hypertension

Brief summary

To identify Predictors of pulmonary hypertension in COPD patients and its relation to different levels of smoking

Detailed description

COPD is a heterogeneous lung condition characterized by chronic respiratory symptoms (dyspnea, cough, expectoration and/or exacerbations) due to abnormalities of the airways (bronchitis, bronchiolitis) and/or alveoli (emphysema) that cause persistent, often progressive, airflow obstruction.It is also the most common cause of deaths in patients with chronic respiratory disease, the fatality rate in USA is 0.41%.Pulmonary Hypertension is the most common serious complication in COPD patients ; which occurs in up to 30% of patients and increases the mortality rate.Smoking is the leading cause of chronic obstructive pulmonary disease (COPD) Smoking is also a trigger for COPD flare-ups.Smoking damages the air sacs, airways, and the lining of your lungs. Injured lungs have trouble moving enough air in and out, so it's hard to breathe

Interventions

DIAGNOSTIC_TESTEchocardiography and HRCT

Echocardiography:is non invasive and easily accessible tool in the diagnosis of any patient with suspected PH.HRCT: is a non-invasive and easily accessible tool to detect pulmonary hypertension in COPD patients.

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 100 Years

Inclusion criteria

* 1.All patients admitted to chest department or presented to our outpatient clinic with clinical and functional diagnosis of COPD among both sexes will be included 2.Age \>18 years Old

Exclusion criteria

* 1.Patients under 18 years old. 2.pregnant patients. 3.patients with history hypertension or valvular diseases 4.Cardiomyopathic patient 5.Patients with concomitant obstructive sleep apnea 6.Patients with collagen vascular disease 7.Patients with thrombo-embolic disease 8. Patients with any chronic chest disease other than COPD

Design outcomes

Primary

Measure	Time frame	Description
Predictors of pulmonary hypertension in COPD patients	1 year	Predict pulmonary hypertension in COPD patients

Secondary

Measure	Time frame	Description
Relationship between different levels of smoking and predictors of degree of pulmonary hypertension	1 year	Levels of smoking (mild.moderate.sever.non smoker) and it's relation to pulmonary hypertension in COPD patients

Contacts

Primary ContactShrouk Mohamed Salah, Resident physician

Shrouksalah806@gmail.com01150637673

Backup ContactMarwan Nasr Sleem, Lecturer of Chest diseases and

faridamarwan2014@yahoo.com01150637673

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026