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Role Of Transthoracic Ultrasound in Predicting Post-extubation Distress During Successful Weaning

Role Of Transthoracic Ultrasound in Predicting Post-extubation Distress During Successful Weaning

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06030401
Enrollment
51
Registered
2023-09-11
Start date
2023-09-01
Completion date
2025-12-01
Last updated
2023-09-11

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Transthoracic US

Brief summary

-To Assess Value of Transthoracic Ultrasound In Predicting Post-extubation Distress in Respiratory ICU Using Ultrasound Parameters As Diaphragmatic Excursion ,Diaphragmatic,Diaphragmatic Thickness Fraction,Diaphragmatic Thickness.

Detailed description

Establishing the correct time to extubate mechanically ventilated patients is a crucial issue in the critical care practice. Both premature and delayed extubation prolong the duration of mechanical ventilation and the intensive care unit (ICU) length of stay and increase morbidity and mortality. Therefore, accurate prediction of post-extubation distress and the early diagnosis of the causes responsible for failure of a trial of pressure support ventilation or a trial of totally unsupported respiration are of paramount importance to improve the outcome of mechanically ventilated patients in the ICU. The Investigators hypothesized that the use of an integrative thoracic ultrasound assessment, encompassing bedside respiratory, and diaphragm sonographic data, could accurately predict post-extubation distress in patients who succeeded in a pressure support ventilation trial. In addition, The Investigators suggest that the use of appropriate analytical methods, that is, machine-learning methods, could permit the evaluation of the specific impact of respiratory and diaphragm sonographic data on the final estimation of a likelihood of post-extubation distress .

Interventions

Sonar of The Chest

Sponsors

Assiut University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum

Inclusion criteria

* Patients above 18 yrs. old who admitted to respiratory ICU and mechanically ventilated due to chest diseases and passed weaning trials

Exclusion criteria

* Pregnancy. * Neuromuscular disorders. * Psychiatric instability. * Uncontrolled cardiovascular disease. * Tracheostomy. * patints with failed weaning trials. * Inability to provide informed consent.

Design outcomes

Primary

MeasureTime frameDescription
post-extubation distressthrough study completion, an average of 3 year.Using Transthoracic US to measure Diaphragmatic Excursion and Diaphragmatic Thickness as Predictors of Postextubation Distress during Successful Weaning Trials.

Secondary

MeasureTime frameDescription
Evaluation of different factors that affect weaning outcome as diaphragmatic dysfunction,ventilator associated pneumonia,electrolyte disturbances and so on.Doing Transthoracic US 48 hour after Starting of Mechanical Ventilation when Patient becomes Weanable during Weaning Trials,and 48 hour Postextubation Weaning and 48 hour postextubation.Looking on Diaphragmatic function And If There is any Ventilator Associated pneumonia And Electrolyte Disturbance

Contacts

Primary ContactRehab Haredy Hassan, Resident Physicion
rehabharedy@gmail.com01026128677
Backup ContactMaha kamel Ghanem, prof
mahaghanem@hotmail.com01227694434

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026