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Hysteroscopic Follow-up Following Conservative Stepwise Surgical Approach for Management of Placenta Previa Accreta

Long-term Follow up of the Cases Who Underwent Conservative Surgery for Placenta Previa Accreta: a Prospective Case Series Study

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06029985
Enrollment
50
Registered
2023-09-08
Start date
2020-06-01
Completion date
2020-12-31
Last updated
2024-01-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Placenta Accreta

Brief summary

Conservative management of placenta accreta spectrum can preserve future fertility but should only be done in hospitals with enough experience as it carries a high risk of maternal complications. Follow up after conservative management is crucial to detect complications early.

Detailed description

Placenta accreta is defined histopathologically as abnormal trophoblast invasion of part or all of the placenta into the myometrium of the uterine wall.1 Depending on the depth of villous tissue invasiveness, placenta accreta was subdivided by pathologists into creta, increta, and percreta, in which the villi adhere superficially to the myometrium without interposing decidua, penetrate deeply into the uterine myometrium, and perforate through the entire uterine wall and may invade the surrounding pelvic organs, respectively. The term placenta accreta spectrum (PAS) will be used in this manuscript to include both the abnormally adherent and the invasive forms of accreta placentation. Severe and sometimes life-threatening hemorrhage, which often requires blood transfusion, increases maternal morbidity and mortality.

Interventions

DIAGNOSTIC_TESTHysteroscopic Follow Up

Office hysteroscopy was carried out to detect the scar site, performed with a 4-mm, continuous-flow operative hysteroscope by vaginoscopic approach, without analgesia or anesthesia. Distension of the uterus was obtained using a normal solution as distension medium, dispensed by an electronic suction/irrigation pump. This can maintain a constant intrauterine pressure of around 30-40 mmHg, balancing an irrigation flow of 200 mL/min with a vacuum of 0.2 bars, necessary to avoid overdistension of the muscle fibers and patient discomfort. The use of this distension medium allows blood or mucus to be washed out from the pouch if necessary.

Sponsors

Ain Shams Maternity Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years

Inclusion criteria

1. Pregnant women with one or more previous cesarean deliveries 2. Women diagnosed with placenta previa accreta and underwent Conservative stepwise surgical approach for management.

Exclusion criteria

1. women who refused to participate in the study. 2. Associated other medical conditions as pregnancy-induced hypertension, heart diseases, and rheumatological diseases apart from iron deficiency anemia. 3. Presence of uterine anomalies

Design outcomes

Primary

MeasureTime frameDescription
Easiness of hysteroscopy introduction3-6 monthsaccessibility of hysteroscopic examination
Adequacy of uterine cavity3-6 monthsvisualization of the uterus will be assessed using office hysteroscopy
intrauterine adhesions3-6 monthsvisualization of the intrauterine adhesions will be assessed using office hysteroscopy
cesarean scar niche3-6 monthspresence of a pouch, that forms on the wall of your uterus.
Menstrual pattern3-6 monthsmenstrual irregularities by history regarding Regular and normal volume or Regular and scanty or presence of Intermenstrual bleeding

Countries

Egypt

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026