Motor Recovery
Conditions
Keywords
tACS, Motor recovery
Brief summary
The overall goal is to investigate the effectiveness of a novel intervention - transcranial alternating current stimulation (tACS) for motor recovery in stroke survivors.
Interventions
Sponsors
The University of Texas Health Science Center, Houston
Study design
Allocation
RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
No
Inclusion criteria
Inclusion/
Exclusion criteria
for stroke subjects Inclusion criteria: 1. Age between 18\~75 years old 2. ≥ 6 months post stroke, medically stable; 3. Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke); 4. Visible finger flexor activation/movement 5. The ability to give consent
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Block and Box Test (BBT) of Motor functional test | Change of BBT performance 5 minutes before and 5 minutes after the tACS intervention will be measured. | The Box and Block Test (BBT) measures unilateral gross manual dexterity. It is a quick and simple test used with a wide range of populations, including clients with stroke. |
| EEG alpha band and Beta band | Change of EEG alpha band and Beta band 5 minutes before and 5 minutes after the tACS intervention will be measured. | Electroencephalography (EEG) is valuable to infer and evaluate the neural interaction. Components of the alpha and beta frequency bands like the sensorimotor rhythm originated from the primary motor cortex and related brain areas reflect human movement. The power of 8-13 Hz alpha and 14-30 Hz beta frequency bands will be used for the classification. |
Countries
United States
Contacts
CONTACTSheng Li, MD, Ph.D
CONTACTShengai Li, MS
PRINCIPAL_INVESTIGATORSheng Li, MD, Ph.D
The University of Texas Health Science Center, Houston
Outcome results
None listed