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Optimising Screening of Intermediate to High-risk Asymptomatic Sportsmen With Exercise Electrocardiogram

Optimising Screening of Intermediate to High-risk Asymptomatic Sportsmen With Exercise Electrocardiogram. The SEEPRED Study.

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06024863
Acronym
SEEPRED
Enrollment
1500
Registered
2023-09-06
Start date
2011-01-01
Completion date
2019-01-01
Last updated
2023-09-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Electrocardiography

Keywords

prediction, sport

Brief summary

The importance of exercise electrocardiogram (ECG) is still controversial in the prevention of cardiac events among sportsmen. The aim of this study was to assess the relevance of exercise electrocardiogram (ECG) as a significant prognostic marker for cardiovascular events when any cardiovascular disease (CVD) risk factors are present.

Detailed description

The SEEPRED (Sport, Exercise ECG, prediction) prospective cohort study included leisure time sportsmen over 35 years old who performed exercise electrocardiogram (ECG) screening in the Sports Medicine Unit of the University Hospital of Saint-Etienne from September 2011 to April 2016. Personal, familial history and physical examination were systematically performed before maximal exercise electrocardiogram (ECG). Cardiovascular events and changes in physical activity were searched after exercise electrocardiogram (ECG).

Interventions

DIAGNOSTIC_TESTScreening stress test on a bicycle ergometer (usual practise)

Sponsors

Centre Hospitalier Universitaire de Saint Etienne
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
MALE
Age
35 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients referred as asymptomatic by their general practitioner for an exercise electrocardiogram (ECG) screening test carried out as a standard procedure for resuming physical activity * Patients referred as a systematic pre-participation screening to be declared an athlete.

Exclusion criteria

* Patients with coronary artery disease (CAD) and * Patients with uninterpretable ST segment due to bundle branch block

Design outcomes

Primary

MeasureTime frameDescription
Silent Myocardial ischemia (SMI)Day 1Determine the frequency of exercise-induced silent myocardial ischemia (SMI).

Secondary

MeasureTime frameDescription
Cardiovascular eventsDay 1Exercise ECG screening test
Gender recordDay 1Gender will be recording during medical consultation in order to predict positive exercise ECG
Age recordDay 1Age will be recording during medical consultation in order to predict positive exercise ECG
Physical activity levels recordDay 1Physical activity levels will be recording during medical consultation in order to predict positive exercise ECG
Treatment recordDay 1Treatment will be recording during medical consultation in order to predict positive exercise ECG
Cardiovascular disease (CVD) risk factors recordDay 1Cardiovascular disease (CVD) risk factors will be recording during medical consultation in order to predict positive exercise ECG
Body mass index recordDay 1Body mass index will be recording during medical consultation in order to predict positive exercise ECG
Score>5% recordDay 1SCORE \>5% will be recording during medical consultation in order to predict positive exercise ECG
Maximal heart recordDay 1Maximal heart rate will be recording during medical consultation in order to predict positive exercise ECG
Maximal aerobic power recordDay 1Maximal aerobic power will be recording during medical consultation in order to predict positive exercise ECG
Maximal blood lactate level recordDay 1Maximal blood lactate level will be collected in order to predict positive exercise ECG
Suspected SMIDay 1Exercise ECG screening test
Confirmed SMIDay 1Exercise ECG screening test

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 6, 2026