Skip to content

Simulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision

Monocular Visual Confusion for Field Expansion

Status
Withdrawn
Phases
Unknown
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06024668
Enrollment
0
Registered
2023-09-06
Start date
2024-08-04
Completion date
2025-01-01
Last updated
2026-07-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Blind Left Eye, Blind Right Eye, One Eye Blindness

Keywords

Simulated Walking, Collision, Field Expansion, One eye blindness

Brief summary

The investigators are developing an assistive device, known as multiplexing prism that expands the field of view for individuals with acquired monocular vision (loss of an eye). The investigators will test the efficacy of the prism in improving the detection of colliding pedestrians during a simulated walking task.

Interventions

Multiplexing prism is designed for spatial vision multiplexing. It allows partial light transmission through the prism allow the observer to simultaneously see the physical world through the prism and see the "shifted view" from the non-seeing side. It is developed to expand the field of view of individuals with just one eye.

Sponsors

Massachusetts Eye and Ear Infirmary
Lead SponsorOTHER
National Eye Institute (NEI)
CollaboratorNIH

Study design

Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE

Intervention model description

Individuals with Acquired Monocular Vision/ Blindness in One Eye

Eligibility

Sex/Gender
ALL
Age
16 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* No medical health issues such as seizures, motor movements problem * Loss of vision in one eye (less than 20/200) for \>1 year * Visual acuity of the seeing eye: Better than 20/32 visual acuity with correction * No visual field defect in the seeing eye (nasal field of at least \>45degree)

Exclusion criteria

* Patients with any physical or mental disabilities, including cognitive dysfunction, balance problems, or other deficits that could impair their ability to respond to the stimuli presented in this study will be excluded * Any person with a history (such as pacemaker use or photosensitive epilepsy) * Any person with motor movements problem (e.g., unable to use extremities)

Design outcomes

Primary

MeasureTime frameDescription
Mean response time to detect colliding pedestrianApproximately 3 sessions, up to 3 hours for each session, any time within 4 month periodThe investigators will compare the mean response time to detect colliding pedestrians coming from the nasal (same side as the blind eye) and temporal (same side as the seeing eye) visual field with and without multiplexing prism. The comparison will be made between these four: Nasal without prism, Temporal without prism, Nasal with prism, and Temporal with prism.

Secondary

MeasureTime frameDescription
Pedestrian Detection RateApproximately 3 sessions, up to 3 hours for each session, any time within 4 month periodThe investigators will measure the rate of correct detection rate of colliding pedestrians in the nasal (same side as the blind eye) and temporal (same side as the seeing eye) with and without multiplexing prism. Comparisons will be made for these: nasal without prism, temporal without prism, nasal with prism,and temporal with prism.

Countries

United States

Contacts

PRINCIPAL_INVESTIGATOREli Peli, OD

Schepens Eye Research Institute

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Jul 10, 2026