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Prospective Cohort Observational Study of Placenta Accreta Spectrum Disorders

Prospective Cohort Observational Study of Placenta Accreta Spectrum Disorders

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06021964
Enrollment
1000
Registered
2023-09-01
Start date
2023-08-28
Completion date
2025-12-07
Last updated
2023-09-01

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Placenta Accreta Spectrum Disorders,Previous Cesarean Section

Keywords

placenta accreta spectrum disorders；Previous cesarean section

Brief summary

The incidence of placenta accreta spectrum disorders has shown an increasing trend worldwide due to the increase of cesarean section rate. Research on the outcomes of placenta accreta spectrum disorders primarily relies on retrospective analysis. The aim of this study was to establish a prospective, multicenter cohort in China in order to conduct further investigations on the clinical features, predictive capabilities, diagnostic methods, and pathogenesis of placenta accreta spectrum disorders.

Interventions

None listed

Sponsors

Peking University Third Hospital
CollaboratorOTHER
Department of Obstetrics and Gynecology, Nanfang Hospital, Southern Medical University
CollaboratorUNKNOWN
Peking Union Medical College Hospital
CollaboratorOTHER
TONGJI MEDICAL COLLEGE OF HUST
CollaboratorUNKNOWN
First Affiliated Hospital of Chongqing Medical University
CollaboratorOTHER
West China Second University Hospital,Sichuan University / West China women's and children's Hospital
CollaboratorUNKNOWN
Peking University First Hospital
CollaboratorOTHER
Guangzhou Medical University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
FEMALE
Age
18 Years to 45 Years
Healthy volunteers
No

Inclusion criteria

1. Pregnant women aged 18-45; 2. at least one previous cesarean section ,regular antenatal examination and plan to give birth at research center 3. sign informed consent

Exclusion criteria

Irregular antenatal examination; Twins; Autoimmune diseases; Prepregnancy hypertension; Prepregnancy diabetes mellitus; Inheritance Sexual diseases; tumor; Abnormal liver and kidney function in early pregnancy

Design outcomes

Primary

MeasureTime frame
Incidence of placenta accreta spectrum disordersbaseline

Secondary

MeasureTime frame
Preterm delivery Preterm deliverybaseline
Blood lost during deliverybaseline
Blood loss in the first 24 hours of deliverybaseline
hysterectomybaseline
Blood transfusionbaseline

Countries

China

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026