Parkinson Disease
Conditions
Keywords
Parkinson Disease, cognitive function, postural balance, physical rehabilitation
Brief summary
This is a prospective study. The aim of this study is to investigate the effect of exercise retraining on cardiorespiratory parameters, postural balance, sociopsychological variables, and cognitive function in subjects with Parkinson's disease. There will be two measurement sessions, one pre-intervention and one post-intervention (measuring cardiorespiratory parameters, evaluating dynamic and static postural balance, and assessing cognitive function).
Detailed description
this is a 12-week prospective study with the theme that I wish to develop in this context entitled the effect of exercise retraining on cardiorespiratory parameters, postural balance, sociopsychological variables, and cognitive function in subjects with Parkinson's disease. There will be two measurement sessions, one pre-intervention and one post-intervention (measuring cardiorespiratory parameters, evaluating dynamic and static postural balance, and assessing cognitive function). The recruited subjects will be randomly assigned to two groups: a control group and an experimental group. The subjects will be invited to attend the program three times per week. The control group will engage in an endurance training program, while the experimental group will participate in a combined endurance training and cognitive training program
Interventions
OTHERrehabilitation
The subjects will be invited to attend the program three times per week.
Sponsors
Faculty of Medicine, Sousse
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
SINGLE (Caregiver)
Eligibility
Sex/Gender
ALL
Healthy volunteers
No
Inclusion criteria
* Diagnosed with Parkinson's disease according to the Movement Disorder Society (MDS) 2015 criteria. * Mild to moderate stage according to the Hoehn and Yahr scale. * No hearing or visual impairments that could hinder the integration and implementation of the rehabilitation protocol. * Has the ability to communicate and walk. * Patient has been stable on treatment for 3 months.
Exclusion criteria
* A contraindication to engaging in cardiovascular physical activity * A Montreal Cognitive Assessment score (MoCA ) of less than 24. * A current psychiatric disorder that could make it difficult or dangerous to adhere to the research protocol. * Musculoskeletal impairments or excessive pain in any joint that could limit participation in an exercise program. * Treatment with sedative medications
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cardiorespiratory Parameters | There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient) | Cardiorespiratory Parameters will be assessed using the six-minute walk test (6MWT). |
| Postural Balance | There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient) | Postural balance will be assessed using the Timed Up and Go test (TUG) and stabilometry platform |
| Depression | There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient) | The depression variable will be assessed through Beck Depression Inventory-II . |
| Cognitive Function | There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient) | Cognitive function will be evaluated using the Montreal Cognitive Assessment score (MoCA) . |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Strength | There will be two measurement sessions, one pre-intervention and one post-intervention (After 12 week for each patient) | handgrip test, Functional Reach Test, Five time to sit and stand test |
Outcome results
None listed