Multiple Sclerosis
Conditions
Keywords
facial pain, craniofacial pain, multiple sclerosis
Brief summary
Although the orofacial pain is not typical symptom of multiple sclerosis, more than 50% of the patients experience some kind of pain. Acute pain usually in form of trigeminal neuralgia, that occurred in 2-3% of patients with multiple sclerosis. Chronic pain occurred in 40-50% of patients and most common forms are headache. Aim of this study is to investigate prevalence and evaluate the form of orofacial pain in patients with multiple sclerosis treated in General hospital Varaždin in period from 01.01. 2017. to 31.12.2022. Results of this investigation will determine better understanding orofacial pain , treatment and impact on everyday life.
Detailed description
Multiple sclerosis is a chronic autoimmune disease with an unknown mechanism of origin. Although pain is not a typical symptom of multiple sclerosis, it occurs in more than 50% of patients and has significant impact on the quality of life of patients. Pain syndromes that patients with multiple sclerosis initially have characteristics of somatic and nociceptive pain, and later neuropathic, including trigeminal neuralgia, headaches, Lhermitte's syndrome. Pain is also often associated with anxiety and depression, which occurs in almost one third of patients. Pain therapy in these patients is a challenge for many doctors involved in the treatment. Many patients do not have adequate pain therapy due to the disproportion between the fear of interaction with other drugs and side effects, and on the other hand the treatment of basic diseases with the aim of controlling the immune response.
Interventions
DIAGNOSTIC_TESTDiagnosis of pain
Pain will be investigated - type, origin, level
Sponsors
Varazdin General Hospital
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
* multiple scerosis * age 18-85 years
Exclusion criteria
* records with missing data
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The frequency of orofacial pain in patients with multiple sclerosis | 3 months | To investigate that, hospital records will be reviewed. Additionally, all of the patients will be approached with the questionnaire investigating the frequency of orofacial pain (expressed in number and proportion of all patients) |
| The location of orofacial pain in patients with multiple sclerosis | 3 months | To investigate that, hospital records will be reviewed. Additionally, all of the patients will be approached with the questionnaire investigating the loacation of orofacial pain |
| The duration of orofacial pain in patients with multiple sclerosis | 3 months | To investigate that, hospital records will be reviewed. Additionally, all of the patients will be approached with the questionnaire investigating the duration of orofacial pain (in months) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Other chronic diseases and orofacial pain | 3 months | To investigate the influence of other chronic diseases on orofacial pain in patients with multiple sclerosis |
| MS therapy's influence to pain | 3 months | To investigate connection between orofacial pain and multiple sclerosis therapy |
| Pain and daily functioning | 3 months | To investigate the impact of pain on the daily functioning of patients with multiple sclerosis |
| MS orofacial pain and the duration of the disease | 3 months | To investigate the connection between orofacial pain and the duration of the disease |
| Pain and patients' characteristics | 3 months | To investigate the pain characteristics in relation to age, sex, form of the disease |
Countries
Croatia
Outcome results
None listed