An Observational Study of Local Relapse After High Grade Osteosarcoma

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06017518

Acronym

OSTEO LR

Enrollment

150

Registered

2023-08-30

Start date

2022-06-13

Completion date

2026-06-30

Last updated

2025-09-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteosarcoma

Brief summary

multicenter retrospective and prospective study in patients with high-grade osteosarcoma

Detailed description

This is a multicenter retrospective and prospective study that will analyze all cases with of diagnosis of local relapse in high-grade osteosarcoma from 01 January 1980 and all new cases referring to each participant site.

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

* Patients who experienced LR as first event of recurrence after treatment for localized high-grade osteosarcoma of bone, including cases with synchronous lung metastases * Adequate patient compliance to follow-up visits * Written informed consent prior to any study-specific analysis and/or data collection * No age limits

Exclusion criteria

* Cases of LR demonstrated after \> 3 months after metastatic disease * Impossibility to ensure adequate compliance

Design outcomes

Primary

Measure	Time frame	Description
post local relapse survival	24 months follow up	the aim of the study is to analyse the factors influencing post local relapse survival

Countries

Italy

Contacts

Primary ContactEmanuela Palmerini, MD

emanuela.palmerini@ior.it051/6366

Outcome results