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Mystical Experience in Hypnosis: a Neurophenomenological Study

A Neurophenomenological Study of Hypnosis

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06017388
Acronym
MystHyp
Enrollment
50
Registered
2023-08-30
Start date
2023-09-01
Completion date
2025-01-31
Last updated
2023-12-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Healthy

Brief summary

Mystical experience is described as an experience that is unique to everyone, potentially transformative and leaving a mark for many years or even a lifetime. It is characterized by: a loss of self/ego, being with the whole/nature/universe, transcendence, a loss of spatio-temporal reference points, ineffability, peace and joy, a sacred character, and a noetic quality. The mystical experience is one that occurs in the context of non-ordinary states of consciousness such as meditation and the consumption of so-called psychedelic drugs, for example. It would seem, in fact, to correspond to the transformative mechanism of the psychedelic experience. The goal ofthis study is to investigate the possibility of a mystical experience through hypnosis.

Detailed description

Anyone interested in taking part in the study will be contacted by telephone or e-mail and offered a face-to-face appointment to carry out the screening (T0). During the appointment, screening (cf. inclusion criteria) will be carried out, socio-demographic data (age, sex, education, nationality, history of hypnosis practice, etc.) and randomization will also take place at this time. At this time, the investigators will assess psychological flexibility and psychologigal well-being, and participants will do a cognitive flexibility task (T1). If people meet the inclusion criteria, the investigators will schedule an appointment for a session to take place roughly a week later. During this session, the investigators will start by reviewing beliefs about hypnosis, assessing participants' expectations of the study, their absorption and dissociation trait, their positive and negative affects and their anxiety. Next, the investigators will perform a 15-minute resting electroencephalographic (EEG) recording. We will then administer the Elkins Hypnotizability Scale. A 30-minute break will be taken. Next, the investigators willperform a hypnotic induction followed by a mystical experience suggestion for the experimental group. The control group will simply receive a reading of the mystical experience suggestion without hypnosis. The rest of the procedure is the same for both groups. EEG activity will be recorded during the mystical experience suggestion (± 15 minutes) in hypnosis and outside hypnosis (ordinary state of consciousness). Directly afterwards, participants will be asked to orally explain their subjective experience during the suggestion of mystical experience. Then the investigators will assess the positive and negative affect in addition to these outcomes: the mystical experience, the ego dissolution, the psychological flexibility, the cognitive flexibility, the altered state of consciousness, the near-death experience, alterness, absorption state, dissociation state, time perception (T2). Three months after receiving the experimental session, participants will be seen again for a follow-up session (T3). During this session, we will ask: Since the experimental session, have you observed any changes in your behaviors, emotions and beliefs? If so, can you tell us about them?. The investigators will assess the positive and negative affects and psychological well-being.

Interventions

BEHAVIORALControl

We will propose the neutral reading of a mystical expetience suggestion (based on Lynn & Evans, 2017).

BEHAVIORALHypnosis

We will propose a hypnotic induction followed by a suggestion of mystical experience (based on Lynn & Evans, 2017).

Sponsors

University of Liege
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
Yes

Inclusion criteria

* at least 18 years old * good comprehension of French

Exclusion criteria

* Psychiatric history * History of neurological disorder * Psychoactive medication * Addiction * Alcoholism

Design outcomes

Primary

MeasureTime frameDescription
Mystical experienceDuring the procedureThe 30-item revised Mystical Experience Questionnaire will assess the occurrence and intensity of mystical-type experiences. It is comprised of four factors: mysticality, positivity of mood, transcendence of time and space, and ineffability. A mystical experience is defined as having a score equal or above 60% on all factors.
HypnotizabilityDuring the procedureThe susceptibility one has concerning hypnosis. Will be assessed with the Elkins Hypnotizability Scale. A score : 0-3 : low hypnotizability 4-7: medium hypnotizability 8-11 : high hypnotizability 12 : very high hypnotizability.

Secondary

MeasureTime frameDescription
Psychological flexibilityBefore the procedure and direclty after the procedureMultidimensional Psychological Flexibility Inventory.
Cognitive flexibilityBefore the procedure and direclty after the procedureCognitive flexility will be assessed with the Test of Attentional Performance which is an informatized cognitive task.
Ego DissolutionDuring the procedureThe Ego Dissolution Inventory will assess the occurrence of ego dissolution.
Modification of mood, cognition, emotion and behaviorAfter 3 monthsWe will ask an open-ended question Since the experimental session, have you observed any changes in your behaviors, emotions and beliefs? If so, can you tell us about them?.
Phenomenal experienceDuring the procedurePhenomenal experience will be assessed by the recording of the narrative experience.
Psychological well-beingBefore the intervention and after 3 monthsPsychological well-being will be assessed with the Warwick-Edinburgh Mental Well-Being Scale
Alteration of consciousnessDuring the procedureThe Phenomenology of Consciousness Inventory will allow to empirically quantify the subjective experience in terms of pattern and intensity parameters. It is composed of 53 items consisting of 12 major dimensions (e.g., positive affect), and 14 minor dimensions (e.g., absorption) (annex). Graphs will be constructed to represent the intensity and pattern of relationships between pairs of dimensions.

Other

MeasureTime frameDescription
Absorption stateDuring the procedureAbsorption will be assessed with a numerical rating scale.
Dissociation stateDuring the procedureDissociation will be assessed with a numerical rating scale.
Socio-demographicsAt screeningage, sex, éducation, nationality, prior practice of hypnosis or other non-ordinary states of consciousness, prior mystical experience.
Time perceptionDuring the procedureWe will ask the participants how long they thought the intervention lasted.
Near Death ExperienceDuring the procedureThe near death experience will be assessed with the The Near-Death Experience Content (NDE-C) Scale.
AlertnessDuring the procedureAlertness will be assessed with a numerical rating scale.
Psychiatric screeningAt screeningPsychiatric screening will be assessed with the Mini-International Neuropsychiatric Interview
Beliefs about hypnosisBefore the procedureBeliefs about hypnosis will be assessed with an open-ended question What are your beliefs about hypnosis?
Expectancies about the studyBefore the procedureExpectancies about the study will be assessed with an open-ended question What are your expectancies about the study?
Phenomenal controlDuring the procedureThe phenomenal control will be assessed with the Phenomenological Control Scale.
Positive and negative affectsBeforethe procedure, During the procedure, direcly after the procedure, and after 3 monthsPositive and negative affects will be assessed with the Positive Affect and Negative Affect.
Absorption traitBefore the procedureThe absorption trait will be assessed with the Tellegen Absorption Scale which consists of 34 true/false items, aiming to measure the absorption of a person, meaning the disposition for having episodes of a deep involvement that engage all the subject's resources (perceptual, imaginative, and cognitive). The total score range is from 0 to 34. The higher the score, the more one has a high propensity for absorption.
Dissociation traitBefore the procedureThe dissociation trait will be assessed with the Dissociative Experience Scale. It is a self-reported questionnaire used to evaluate the presence, quantity, and type of dissociative experiences one might live in daily life. It consists of 28 items arranged on an analog scale (from 0 to 100% measuring the frequency of dissociative experiences), and the total score ranges from 0 to 100. There is a cutoff of 45 as a mean score to suggest a dissociative disorder. This questionnaire is not a diagnostic instrument; it is designed only for screening, but it can suggest that a specific clinical assessment is needed.
Anxiety stateBefore the procedure and during the procedureAnxiety will be assessed with a numerical rating scale.

Countries

Belgium

Contacts

Primary ContactAminata Bicego
abicego@uliege.be+3243663499
Backup ContactAudrey Vanhaudenhuyse
avanhaudenhuyse@chuliege.be+3243238033

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026