Ulcerative Colitis
Conditions
Keywords
Hematuria, Urine, 5-Aminosalycilic acid
Brief summary
The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA
Detailed description
The aim of this study is to evaluate the effect on urine color by adding household bleach to fresh urine sample among pediatric UC subjects treated with 5ASA.
Interventions
OTHERAdding household bleach to urine sample
Adding household bleach to urine sample
Sponsors
Meir Medical Center
Study design
Allocation
NON_RANDOMIZED
Intervention model
PARALLEL
Primary purpose
SUPPORTIVE_CARE
Masking
SINGLE (Caregiver)
Eligibility
Sex/Gender
ALL
Age
4 Years to 20 Years
Healthy volunteers
No
Inclusion criteria
1\. UC patients in remission
Exclusion criteria
1. Acute UC exacerbation defined as Pediatric ulcerative colitis activity index (PUCAI) ≥10 2. Any acute or chronic renal disease, either present or past 3. Chronic hypertension, either present or past 4. Regularly receiving other medication that may cause nephrotoxicity - Non-steroidal anti-inflammatory drugs, acetaminophen, anti-epileptics, and antibiotics. 5. Pregnancy
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change is urine color | 5 minutes | Following the addition of 1mL of 5% household bleach to a 10mL of each subject's urine, we will visually look for color change to red or orange within 5 minutes. Urine changing color to red or orange will be marked as a positive response to the bleach, which would fulfill the primary outcome. |
Countries
Israel
Outcome results
None listed