Cardiac Surgical Procedures
Conditions
Brief summary
Retrospective collection of Wuhan Union hospital from December 1,2018 to June 30,2021 to meet the entry and discharge standards. The patient 's medical record data were divided into study group and control group according to the use of gastrodin during operation. The perioperative data and prognostic outcomes in the patient 's medical records were collected and analyzed. The degree of myocardial injury and postoperative clinical outcomes were compared between the two groups.
Interventions
None listed
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Study design
Observational model
COHORT
Time perspective
RETROSPECTIVE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Patients aged≥18 years, regardless of gender; * Patients undergoing elective cardiac surgery under general anesthesia; * ASA grade 1 \ 3.
Exclusion criteria
* Suffering from more serious genetic diseases (such as immunodeficiency, thalassemia, etc.); * Moderate to severe malnutrition, moderate to severe anemia; * Persistent infection; * Severe preoperative underlying diseases (such as severe liver and kidney dysfunction)
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The degree of myocardial injury | The myocardial tissue was collected during the operation. About 2 hours on average | The myocardial tissue trimmed by the surgeon according to the surgical requirements was collected during the operation for electron microscopy observation and detection of related molecular content. |
Countries
China
Outcome results
None listed