Carpal Tunnel Syndrome Evaluation With Ultrasound in Rheumatoid Arthritis Patients

Ultrasound Evaluation of the Median Nerve in Patients With Rheumatoid Arthritis and Its Relationship With Disease Activity

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06012630

Enrollment

Registered

2023-08-25

Start date

2023-01-15

Completion date

2023-08-15

Last updated

2023-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Median Nerve Entrapment

Keywords

Rheumatoid arthritis, Ultrasound, Carpal Tunnel Syndrome

Brief summary

In rheumatoid arthritis (RA) patients, the diagnosis of Carpal tunnel syndrome (CTS) was made based on clinical findings and physical examinations. Then, the cross-sectional areas of the participants' median nerves from different levels were measured. Meidolateral and anteroposterior diameter were measured at the level of the carpal tunnel inlet. Flattening ratio was calculated. wrist to forearm ratio and wrist to forearm difference were calculated. The obtained data were compared between RA with CTS, RA without CTS and healthy control.

Interventions

DIAGNOSTIC_TESTUltarsound

Median nerve evaluation of participants with ultrasound

Study design

Observational model

COHORT

Time perspective

CROSS_SECTIONAL

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Yes

Inclusion criteria

* RA patients identified according to the 2010 American College of Rheumatology/Europan Leage Against Rheumatism classification criteria * healthy controls (HC) with no history of rheumatic diseases and CTS. * Individuals aged 18-65 years.

Exclusion criteria

* thoese with hypothyroidism, * gout, * diabetes mellitus, * history of CTS surgery, * upper extremity plexopathy, * polinöropathy, * uncontrollable fibromyalgia, * steroid injection for CTS * For the HC group, those with phalen or tinnel detected in at least one wrist and those with bifid median nerve detected during US evaluation were not included in the study.

Design outcomes

Primary

Measure	Time frame	Description
Comparison of US findings among participants	6 months	Comparison of US findings among participants

Secondary

Measure	Time frame	Description
Relationship between US findings and disease activity in the patient group	6 months	The correlation between the US findings of the participants in the patient group and the CDA, which evaluates disease activity, was examined.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026