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QRS Microfragmentation in ECG as Predictor of Mortality and Morbidity - a Retrospective Analysis

QRS Microfragmentation in ECG as Predictor of Mortality and Morbidity - a Retrospective Analysis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06011590
Enrollment
150000
Registered
2023-08-25
Start date
2000-01-01
Completion date
2022-07-31
Last updated
2023-08-25

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Risk Stratification

Brief summary

Over the past decades, several ECG-based parameters have been identified as independent predictors of worsened prognosis in affected patients. In addition to visual assessment of morphology, methods of computer-based machine ECG analysis have gained importance in recent years. These methods allow the detection of systemic abnormalities in ECGs that are not visible to the naked eye. An example of this is provided by the so-called QRS microfragmentations. The aim of this evaluation is to retrospectively collect all established as well as new quantitative and qualitative ECG parameters (such as QRS microfragmentation) in a large patient collective. Subsequently, after characterization of the patients, an independent multivariate risk prediction model should be developed based on computer-based ECG analysis using maschnine learning algorithms.

Interventions

OTHERNo intervention.

No intervention.

Sponsors

Medical University Innsbruck
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes

Inclusion criteria

* Patients who presented to the Department of Internal Medicine at the Medical University in Innsbruck between 01.01.2000 and 31.07.2022 and received an ECG recording as part of routine clinical practice. * Age ≥ 18 years * Residence in Austria

Exclusion criteria

* Insuffizient ECG Recording quality

Design outcomes

Primary

MeasureTime frameDescription
All cause mortalitybetween 01.01.2000 and 31.07.2022Death of any cause

Secondary

MeasureTime frameDescription
Hospitalizationbetween 01.01.2000 and 31.07.2022Unplanned Hospitalization
Lenght of hospital staybetween 01.01.2000 and 31.07.2022Lenght of hospital stay

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026