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Validating a Clinical Decision Support Tool for Stratifying Stroke Risk for Dizziness/Vertigo

Validating a Clinical Decision Support Tool for Stratifying Stroke Risk in Patients Presenting With Dizziness to the Emergency Department

Status
UNKNOWN
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT06010550
Enrollment
600
Registered
2023-08-24
Start date
2023-10-01
Completion date
2025-12-31
Last updated
2023-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Dizziness, Vertigo

Keywords

Dizzy, Vertigo, Stroke, Machine learning

Brief summary

This study aims to validate a machine learning model that stratifies the risk of stroke in patients who present to the emergency department with dizziness or vertigo.

Detailed description

This is a cross-sectional, hospital-based study, with no randomization procedure. Over a 21-month period, approximately 600 subjects will be enrolled. The study will assess the risk of stroke in each patient using a machine-learning model. To detect ischemic or hemorrhagic stroke, each patient will undergo a non-contrast brain magnetic resonance imaging study. The predictive performance of the machine-learning model will be evaluated in terms of accuracy, precision, recall, F1 score, and area under the receiver operating characteristics curve.

Interventions

RADIATIONMagnetic resonance imaging

Brain magnetic resonance imaging

Sponsors

National Science and Technology Council
CollaboratorFED
Chiayi Christian Hospital
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
ALL
Age
20 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* Presenting to the emergency department with dizziness or vertigo * Aged ≥ 20 * Dizziness or vertigo lasting for at least 1 hour and \< 7 days * Persistent dizziness or vertigo at the time of the examination at the emergency department

Exclusion criteria

* Having 5 or more prior episodes similar in quality, intensity, and duration to the current symptoms, with at least one episode more than a year prior and one within the past year * Having frank stroke-like symptoms or signs, such as hemiparesis, facial asymmetry, dysarthria, dysphasia, ataxia, gaze palsy * Consciousness disturbance, Glasgow coma scale \< 13 * Severe dementia * Recent stroke within 3 months * Dizziness or vertigo thought to be the result of head injury, hypotension, medication/drug intoxication, hypoglycemia, electrolyte imbalance, anemia, hepatic encephalopathy, hydrocephalus, etc * Concomitant head or neck trauma * Severe degenerative cervical spondylosis * Having contraindications to magnetic resonance imaging examination

Design outcomes

Primary

MeasureTime frameDescription
Number of participants with strokeBetween 24 hours and 14 days after the emergency department visitNumber of participants with ischemic or hemorrhagic stroke confirmed by brain magnetic resonance imaging

Contacts

Primary ContactSheng-Feng Sung, MD, PhD
sfsung@cych.org.tw886-5-2765041

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026