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Osteogenesis Imperfecta and Balance

Efficacy of Whole Body Vibration on Balance and Motor Control in Children With Osteogenesis Imperfecta

Status
UNKNOWN
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06010134
Enrollment
60
Registered
2023-08-24
Start date
2023-05-01
Completion date
2023-09-30
Last updated
2023-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteogenesis Imperfecta

Keywords

Osteogenesis Imperfecta, Whole Body Vibration, Balance, Motor Control

Brief summary

Osteogenesis Imperfecta (OI), also known as brittle bone disease, is a group of genetic disorders that mainly affect the bones. It results in bones that break easily. Its severity may be mild to severe. Other symptoms may include a blue tinge to the whites of the eye, short height, loose joints, hearing loss, breathing problems and problems with the teeth. Physiotherapy is aimed to strengthen muscles and improve motility in a gentle manner, while minimizing the risk of fracture, and the use of support cushions to improve posture.

Detailed description

This study aimed to assess the efficacy of Whole Body Vibration on balance and motor function in children with Osteogenesis Imperfecta. Whole body vibration (WBV) therapy is targeted at musculoskeletal strengthening and has been trialed in a variety of conditions. WBV has been shown to have therapeutic advantage in various osteopenic preclinical models and populations such as postmenopausal women (improved mobility, muscle strength, postural strength, and bone density) and children with osteogenesis imperfecta (improved mobility)

Interventions

OTHERPhysical Therapy Program

Physical Therapy Program plus Whole Body Vibration

Sponsors

South Valley University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Masking description

Double (Participant, Investigator) Single (Outcomes Assessor) Blinding process to participants and care providers was impossible due to the nature of intervention therapy. Data were analyzed by an impartial statistician (outcomes assessor), referring to each arm with an encoded name: Group 1 (control group) and Group 2 (Whole Body Vibration group).

Intervention model description

G 1 (control) received traditional physical therapy program for 30 min. G 2 (study) received traditional physical therapy program for 15 min. and Whole Body Vibration for 15 min

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

1. Their age was ranging from six to twelve years 2. Children participated in this study were from both sexes 3. All children with stable medical and psychological status. 4. They were able to follow the verbal commands or instructions during testing.

Exclusion criteria

1. Children with visual or auditory problems. 2. Children with any cognitive problems. 3. Children without deformity

Design outcomes

Primary

MeasureTime frameDescription
Over All Stabiity Indexat day 0Stability Index
Medio lateral Stabiity Indexat day 0Stability Index
Antro posterior Stabiity Indexat day 0Stabiity Index

Countries

Egypt

Contacts

Primary ContactNehad Abo-zaid, Assistant Professor
dr.nehadahmed@svu.edu.eg+201008980727

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026