Pregnancy Related, Uterine Fibroid
Conditions
Keywords
Uterine fibroids, Pregnancy, myomectomy, fetal outcomes
Brief summary
The frequency of women presenting with a combination of uterine fibroids and pregnancy is in-creasing nowadays. Uterine fibroids in pregnancy are an unfavorable condition in themselves and being reactive to hormonal stimuli, tending to grow, can generate symptoms of different lev-els of severity. Obstetrics and gynecologists are increasingly faced with the problem of clarifying the management tactics of pregnant patients with symptomatic fibroids, who may see their preg-nancy put at risk by these masses.
Interventions
PROCEDURELaparotomic myomectomy during pregnancy
Surgical removal of symptomatic uterine fibroids in pregnancy by laparotomic access
Sponsors
University of Palermo
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* The large and giant size of UFs, which prevent the proper continuation of pregnancy and/or occupy the entire small and large pelvis, as well as invade and/or occupy the abdominal cavity. * Circulatory disorders, evidenced by necrosis of the UFs. * Atypical localization of UFs (cervical, isthmic, intraligamentary, etc.), which caused pelvic organ dysfunction (dysuric phenomena, tenesmus, impediment to the act of defecation, pelvic pain).
Exclusion criteria
* Refusal of LPTM by the patient. * Absence of urgent indication for LPTM during pregnancy.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| continuation of pregnancy | 5 months | Pregnancy continuation after surgery. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Fetal outcome | 5 months | Assessed by APGAR 1 and 5 min, birth weight, and fetal conformation. |
Countries
Russia
Contacts
Primary ContactAndrea Etrusco, M.D.
Outcome results
None listed