VTE Incidence After Curative Colon Cancer Surgery in an ERAS Program

Incidence of Venous Thrombotic Event After Curative Colon Cancer Surgery in an Enhanced Recovery After Surgery Program

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT06009484

Enrollment

2141

Registered

2023-08-24

Start date

2014-01-01

Completion date

2018-03-15

Last updated

2023-08-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colon Cancer, Deep Vein Thrombosis, Pulmonary Embolus

Keywords

Prolonged thromboembolic prophylaxis

Brief summary

Based on data on a cohort of 2,141 patients undergoing elective colonic cancer resection in an ERAS program, the incidence of postoperative thromboembolic events is estimated in patients no receiving prolonged thromboembolic prophylaxis.

Detailed description

The Copenhagen cOmplete Mesocolic Excision Study (COMES) database contains comprehensive data on preoperative, intraoperative, postoperative and tumor related variable on patients undergoing elective colonic cancer resection at four public university clinics providing all colorectal cancer treatment for the 1.8 million residents of the Capital Region of Denmark during the period 2014-2017. None of these hospitals had implemented prolonged thromboembolic prophylaxis after discharge. The medical records were reviewed with focusing on VTE prophylaxis, ongoing preoperative and postoperative anticoagulant treatment, the length of hospital stay (LOS), and readmission to ensure high data validity.

Interventions

PROCEDUREColon resection

Colon cancer resection

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to No maximum

Healthy volunteers

Inclusion criteria

* elective macroradical resection for UICC Stage I-III colonic adenocarcinoma

Exclusion criteria

* concomitant rectum resection * soly appendix carcinoma * diagnosed with pulmonary embolism or deep venous thrombosis before primary discharge * dying before discharge from the hospital or discharged at postoperative day 28 or later * treatment with vitamin K antagonists, heparin or new oral anticoagulants before or after surgery * VTE less than 3 months before the colon resection

Design outcomes

Primary

Measure	Time frame	Description
Postoperative venous thromboembolic event	60 days	Deep venous thrombosis or pulmonary embolism

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026