Complex Post-Traumatic Stress Disorder
Conditions
Keywords
EMOTION REGULATION
Brief summary
This study will examine context sensitivity, composed of two sequential elements: (a) accurate classification of changing affective contextual demands, followed by (b) flexible selection of regulatory strategies that matches changing contextual demands, among complex PTSD vs. Healthy controls.
Detailed description
The study will recruit adults with posttraumatic stress disorder (PTSD) due to a repetitive inter-personal trauma and healthy adult controls which do not meet DSM-5 criteria for PTSD and do not meet the clinical cutoff of Anxiety and Depression screening questionnaires. A compatibility check, filtering, verification of exclusion criteria and informed consent will occur via online self-report questionnaires. Clinical questioners include: Life event Checklist (LEC) - PTSD criteria A Post-trauma Checklist for DSM-5 (PCL) - PTSD symptoms Patient Health Questionnaire (PHQ-9) - Depression Symptoms General Anxiety Disorder Questioner (GAD-7) - Anxiety Symptoms Participants who pass the initial filtering, will be called and provided with an explanation about the study following which they received the online experiment. Modified regulatory selection flexibility paradigm- included 3 blocks: (A) Stimuli Classification- 80 emotional words (equally distributed between high or low intensities) are presented and participants are asked classify each emotional word to high or low intensity. (B) Regulatory Selection- 40 emotional words (out of the 80 presented in block A) are presented and participants are instructed to behaviorally choose between distraction and reappraisal. (B) Regulatory Selection- 40 emotional words (the 40 remaining from block A) are presented, prior to regulatory selection, participants received accurate normed intensity classification of the word and then participants are instructed to behaviorally choose between distraction and reappraisal.
Interventions
BEHAVIORALContext Sensitivity in Emotion Regulation
Context Sensitivity of affective intensities and its association to Emotion Regulation Flexibility Selection
Sponsors
Gal Sheppes
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
BASIC_SCIENCE
Masking
NONE
Intervention model description
2 groups enrolled in a one-time behavioral paradigm
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
Yes
Inclusion criteria
* Native Hebrew speakers * age between 18 - 65 * normal or corrected to normal vision * computer and internet access * Group 1: Diagnosis of PTSD according to the DSM-5 * Group 2: GAD and PHQ scores (score\<10), no diagnosis of PTSD according to the DSM-5
Exclusion criteria
* Psychosis * substance dependence or abuse other than nicotine * Neurological condition
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Difference in accurate intensity classification measured during Block A of the experiment | During the experimental task (1 hour) | comparing the accuracy in intensity classification of 80 words stimuli between the PTSD group and the control group. |
| regulatory selection flexibility (distraction choice in high intensity minus distraction choice in low intensity) as assessed by regulatory selection paradigm | During the experimental task (1 hour) | group comparison of the association between accuracy in intensity classification (as measured in Block A) and regulatory selection flexibility (measured by the flexibility score which is calculated by subtracting the proportion of distraction selection in the low intensity stimuli (which reflects maladaptive behavior) from the proportion of distraction selection in the high intensity pictures (which reflects adaptive behavior) measured in Block B. |
| regulatory selection flexibility (measured by distraction choice in high intensity minus distraction choice in low intensity) following provided intensity as assessed by regulatory selection paradigm | During the experimental task (1 hour) | group comparison of the association between provided intensity classification (i.e., whether stimuli is of high or low intensity) and regulatory selection flexibility (measured by the flexibility score which is calculated by subtracting the proportion of distraction selection in the low intensity stimuli (which reflects maladaptive behavior) from the proportion of distraction selection in the high intensity pictures (which reflects adaptive behavior) measured in Block C |
Countries
Israel
Outcome results
None listed