Total Knee Replacement, Wound Complication
Conditions
Brief summary
Wound complications after total knee arthroplasty (TKA) can arise from many patient-specific factors, such as vascular or immune-related medical conditions, obesity, and smoking, among others. The development of early wound complications can lead to increased length of hospital stay and more serious complications, including deep infection and major subsequent surgery. However, there are modifiable variables that could affect the risk of getting wound complications, such as the closure technique. This study aims to analyze the difference in rates of wound complications using two different closure techniques in primary TKA.
Interventions
PROCEDURESkin closure using skin adhesive
Wound closure using subcuticular running 3-0 monocryl sutures with skin adhesive
PROCEDURESkin closure without skin adhesive
Wound closure using subcuticular running 3-0 monocryl sutures without skin adhesive
Sponsors
Rothman Institute Orthopaedics
Study design
Allocation
NON_RANDOMIZED
Intervention model
CROSSOVER
Primary purpose
TREATMENT
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Patients older than 18 years old that will undergo primary TKA with a midline approach
Exclusion criteria
* Previous knee arthroplasty surgeries or midline scars * TKA secondary to oncologic or traumatic etiologies * BMI ≥ 40 * uncontrolled diabetes (measured by a Hgb A1c above 8) * reported allergy to skin adhesive * immunodeficiencies * bleeding disorders * anticoagulation other than ASA
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| wound complications | 90 days | Assessed using Photographic documentation of the wound |
| Patient satisfaction | 90 days | Assessed using the POSAS (patient and observer scar assessment scale) questionnaire |
Countries
United States
Outcome results
None listed