Post-stroke Dementia
Conditions
Keywords
randomized controlled trial, post-stroke dementia, Acupuncture, nimodipine
Brief summary
To observe the clinical efficacy of TCM acupuncture combined with western medicine nimodipine for prevention of post-stroke dementia by comparing with clinical conventional treatment methods.
Interventions
DRUGThe control group received oral nimodipine tablets
The control group received oral nimodipine tablets
Sponsors
Department of acupuncture and massage, Nanling Hospital of traditional Chinese Medicine, Nanling County, Wuhu City, Anhui Province
Yuzhen Pan
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
SINGLE (Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
40 Years to 85 Years
Healthy volunteers
No
Inclusion criteria
1. Definite ischemic stroke or hemorrhagic stroke confirmed by head CT / MRI examination 2. Memory or cognitive and executive dysfunction. Cognitive dysfunction will be determined after the mini mental state evaluation (MMSE) score 3. Age limited to 40-85 years, irrespective of gender 4. Stable condition, clear consciousness, no aphasia, oral medication available 5. No major comorbidity, no major depression 6. Consent and signed patient informed consent
Exclusion criteria
1. Had serious medical conditions, such as heart, liver, kidney, or endocrine disease 2. Aphasia or hearing impairment 3. Participants in other clinical trials 4. Patients currently on medication to improve cognitive function
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Response Rate | 24 weeks |
Secondary
| Measure | Time frame |
|---|---|
| Hasegawa Dementia Scale | 24 weeks |
| Montreal Cognitive Assessment | 24 weeks |
Countries
China
Outcome results
None listed