Effective Intracanal Medicaments Against Enterococcus Faecalis
Conditions
Brief summary
this study aims to evaluate the antimicrobial efficacy of two synthetic (Ibuprofen, Modified triple antibiotic paste) and two herbal materials (Curcumin and Olive leaves extract) used as intracanal medication, against E.Faecalis in secondary endodontic infection cases.
Detailed description
we evaluate the antimicrobial efficacy of two synthetic (Ibuprofen, Modified triple antibiotic paste) and two herbal materials (Curcumin and Olive leaves extract) used as intracanal medication, against E.Faecalis in secondary endodontic infection cases by taking three samples from root canal , the first sample after removing gutta percha from root canal system, the second sample after shaping with protaper universal files and cleaning with 2.5% sodium hypochlorite , the third sample after 7 days from application of the medication . samples will be diluted into ten fold serial dilution and then the diluted samples will be cultured on bile esculin agar as it is selective media for enterococcus feacalis. bacterial reduction will be determined and comparision will be made .
Interventions
DRUGIbuprofen 400 mg.
synthetic intracanal medicament
synthetic intracanal medicament
DIETARY_SUPPLEMENTcurcumin
herbal intracanal medicament
DIETARY_SUPPLEMENTolive leaves extract
herbal intracanal medicament
Sponsors
Tanta University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)
Eligibility
Sex/Gender
ALL
Healthy volunteers
Yes
Inclusion criteria
* Single rooted teeth. * Teeth have clinical signs and symptoms of endodontic failure as sensitivity to percussion, pain, swelling or fistula. * Teeth with radiographic features of endodontic failure as persistent periapical lesion or widening of periodontal ligament.
Exclusion criteria
* • Teeth with fractures of the crown or root. * Teeth with periodontal pocket deeper than 4mm. * Teeth have procedural error like ledge, broken instrument, or perforation.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| measurment of microbial reduction as result of applying synthetic and herbaal intracanal medicaments | time necessary for incubation of each sample is 24 hour | sample 1 will be taken after gutta percha removal sample 2 will be taken after cleaning and shaping sample 3 will be taken after apllying the intracanal medicament for one week |
Contacts
Primary Contactalaa essam abo laimon, demonstrator at university
Outcome results
None listed