Cardiovascular Diseases in Pregnancy
Conditions
Brief summary
Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed. Ejection fraction (EF) was quantified using biplane Simpson's method.
Detailed description
Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed, including parasternal long and short, apical 4- and 2-chamber views. Continuous wave and pulse wave Doppler were used to assess left ventricular outflow tract (LVOT) gradients. Left ventricular (LV) function was quantified using biplane Simpson's method and visually assessed by two independent readers. Patients with significant valve disease or congenital heart disease underwent complete TTE. Those diagnosed with LV dysfunction or other cardiovascular diseases (CVD) were referred to the Cardio-Obstetrics clinic for further management and long-term follow-up.
Interventions
None listed
Sponsors
Jinnah Postgraduate Medical Centre
National Institute of Cardiovascular Diseases, Pakistan
Study design
Observational model
COHORT
Time perspective
PROSPECTIVE
Eligibility
Sex/Gender
FEMALE
Healthy volunteers
No
Inclusion criteria
* Obstetric patients attending routine antenatal visits
Exclusion criteria
* Patients refused to give consent for echocardiography or participation in the study
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants found to have abnormal left ventricular function | At the time of screening echocardiogram | Prevalence of Left ventricular dysfunction (Ejection Fraction\<55%) |
| Number of participants found to have abnormal heart valve function | At the time of screening echocardiogram | Structural heart abnormalities (valvular heart lesions classified as mild, moderate and severe) |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Number of participants found to have adverse Maternal outcomes | At the time of delivery | Maternal Mortality, Cardiogenic shock |
| Number of participants found to have adverse Fetal outcomes | At the time of delivery | Infant Mortality, Infant birth weight (kg) |
Countries
Pakistan
Contacts
Primary ContactSabha Bhatti, MD
Backup ContactShakeela Naz, FCPS
Outcome results
None listed