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Medication Adherence in Kidney Transplant

Impact of Text Message Reminders on Immunosuppressive Medication Adherence Among Kidney Transplant Recipients: A Randomized Controlled Study

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06004102
Enrollment
100
Registered
2023-08-22
Start date
2021-01-01
Completion date
2023-02-08
Last updated
2023-08-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Medication Adherence

Keywords

kidney transplantation, reminder text messages, medication adherence, surgical nursing

Brief summary

Aims and Objective: The study aimed to assess the impact of text message reminders on medication adherence among kidney transplant recipients. Background: One of the most common problems encountered in transplant patients is incompatibility with immunosuppressive drugs, one of the most important reasons for graft rejection. Design: A randomized controlled trial was conducted from January to October 2021 and conducted in accordance with the Consolidated Standards of Reporting Trials 2010 guidelines. Methods: This randomized controlled trial included a total of 100 patients receiving a kidney transplant, 50 in the intervention group and 50 in the control group. Patients in the intervention group were sent text message reminders four times a day during the 6th to 9th months after transplantation. Control patients received no such intervention. Tacrolimus concentrations in the bloodstream were monitored for all participants through measurements taken at months 7,8, and 9. Data collection tools included Sociodemographic and Descriptive Characteristics Form and Immunosuppressive Medication Adherence Scale. Research hypotheses H1- Sending text message reminders improves immunosuppressive medication adherence in kidney transplant recipients. H2- Utilization of text messages as reminders has a significant influence on tacrolimus blood profiles in kidney transplant recipients. H3- There is a correlation between the scores from the Immunosuppressive Medication Adherence Scale and mean tacrolimus plasma levels in kidney transplant recipients. H4- There is a correlation between the sociodemographic and descriptive characteristics of kidney transplant recipients and their mean scores from the Immunosuppressive Medication Adherence Scale.

Interventions

OTHERreminder text message

The study aimed to assess the impact of text message reminders on medication adherence among kidney transplant recipients.

Sponsors

Akdeniz University Hospital
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* 18 years or older * Being a recipient of a kidney transplant for the first time * Being a kidney transplant recipient at post-transplant month 6 with scheduled follow-up until month 9 * Ongoing immunosuppressive drug therapy * Absence of any disability that hinders communication * No diagnosis of psychological and mental problems * Being an active cell phone user * Ability to read and write * Voluntary participation in the research.

Exclusion criteria

* Hospitalization for any reason during the research period * History of combined or dual organ transplantation.

Design outcomes

Primary

MeasureTime frameDescription
The effect of sending reminder text messages on immunosuppressive medication adherencebaseline and 9 monthsThe IMAS is a validated an 11-item self-report questionnaire developed in 2015 to measure medication adherence in patients that have received solid organ transplants and are prescribed immunosuppressive drugs.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026