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Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.

Comparison Of The Outcome Of Treatment of Microneedling With Autologous Platelet- Rich -Plasma Versus Microneedling With Topical Insulin In The Treatment Of Post Acne Atrophic Scars.

Status
Completed
Phases
Phase 2
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT06002854
Enrollment
50
Registered
2023-08-21
Start date
2022-08-01
Completion date
2023-02-01
Last updated
2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

ATROPHIC ACNE SCARS

Brief summary

Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9

Interventions

DRUGPRP( platelet rich plasma) and Insulin human

Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

Sponsors

Jinnah Postgraduate Medical Centre
Lead SponsorOTHER_GOV

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
NONE

Eligibility

Sex/Gender
ALL
Age
20 Years to 50 Years
Healthy volunteers
Yes

Inclusion criteria

* postacne atrophic scars ≥ 2 on Goodman and Baron's acne scar-grading system * Either gender. * Age 20-50 years.

Exclusion criteria

* lactation and pregnancy * skin cancers and infection * photosensitivity like SLE ,XP * use of RETINOIDS in last 6 months.

Design outcomes

Primary

MeasureTime frameDescription
Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scarsEfficacy will be assesed upto 4 months.Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System

Countries

Pakistan

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026