Ataxia, Multiple Sclerosis
Conditions
Keywords
Multiple Sclerosis, ataxia, coordination, life kinetic exercises
Brief summary
Coordination is essential for the performance of most daily motor activities. Coordination problems are common in MS patients. One of the most commonly reported symptoms is dysmetria (limb ataxia). Ataxia is thought to occur in about 80% of MS patients. It leads to limitations in daily life activities. Aim of Study: to investigate the effect of life kinetik training on lower limb coordination in MS patients with ataxia.
Detailed description
Methods: Thirty remitting relapsing Multiple Sclerosis (RRMS) patients from both sexes with ataxic symptoms, will be recruited from multiple sclerosis specialized clinic in the Neurology department, Faculty of Medicine, Cairo University with EDSS score will be ranged from 2 to 4 and SARA score will be ranged from 1 to 10. Lower Extremity Motor Coordination Test (LEMOCOT) will be used to assess lower limb motor coordination. They will be randomly assigned into two equal groups; control group (GI) will receive selected physical therapy program and study group (GII) will receive same program of (GI) in addition to life kinetik training.
Interventions
OTHERphysical therapy
Frenkel's exercises for lower limb, Proprioceptive neuromuscular facilitation for upper limb in the form of rhythmic stabilization
OTHERlife kinetic exercises
A multimodal training that combines coordinative, cognitive and visual tasks.
Sponsors
Cairo University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
DOUBLE (Subject, Outcomes Assessor)
Intervention model description
randomized controlled trail
Eligibility
Sex/Gender
ALL
Age
20 Years to 45 Years
Healthy volunteers
No
Inclusion criteria
* MS from both sexes * Patients' age will be ranged from 20 to 45 years * Expanded disability scale (EDSS) score ranging from two to four
Exclusion criteria
* Patients with Ataxia caused by other cause rather than MS * Patients with other neurological disease or orthopedic deformities may affect movement * Patients with cardiovascular and pulmonary diseases that make exercise unsafe * Patients with cognitive impairment or psychiatric disorders
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Lower Extremity Motor Coordination Test (LEMOCOT) | at baseline | test to assess lower limb coordination |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Four Square Step Test (FSST) | at baseline | test to assess dynamic balance |
Countries
Egypt
Outcome results
None listed