Airway Clearance Impairment
Conditions
Keywords
Intrapulmonary percussive, Healthy volunteer, pulmonary function, Electrical Impedance Tomography
Brief summary
The goal of this clinical trial is to prove the benefit of intrapulmonary percussive ventilator in healthy volunteers. The main questions are: * How can intrapulmonary percussive improve lung function？ * What is the subjective feeling through intrapulmonary percussive? Participants will be undergoing treatment of intrapulmonary percussive. Then they will be assessed for lung function and EIT before and after intrapulmonary percussive.
Interventions
DEVICEIntrapulmonary Percussive ventilator
The volunteers will undergo three minutes low frequency and high frequency intrapulmonary percussive treatments.
Sponsors
Shanghai 10th People's Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
SUPPORTIVE_CARE
Masking
NONE
Eligibility
Sex/Gender
MALE
Age
18 Years to 40 Years
Healthy volunteers
Yes
Inclusion criteria
* No respiratory system, heart disease * Well cooperate with the MateNeb
Exclusion criteria
* No respiratory illness such as influenza, pneumonia, asthma, bronchitis within the last month * Couldn't finish three times pulmonary function test
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Pulmonary function test | through study completion, an average one hour | This test can assess the volunteer's lung ventilation and diffusion function.For example the max vital capacity (VCMAX),Forced vital capacity(FVC),Forced expiratory volume in one second(FEV1),functional residual capacity(FRC-SB),diffusion capacity of lung for carbon monoxide(DLCO) and so on. |
| Electrical Impedance Tomography of Pulmonary(EIT) | through study completion, an average one hour | EIT is a relatively advanced non-invasive monitoring technique for the lung function. This technology uses a strap attached to the chest to monitor electrical at 16 locations. The Ventilation in each area resistance of the lung is quantified according to the electrical resistance |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The safety and comfort | The treatment was scored once after the participants completed both low and high frequency intrapulmonary percussive.Up to one week. | Whether the technique has adverse reactions. How do the volunteers feel? We used a scale of 1 to 4 to show how the volunteers felt. 1 is the worst feeling. The volunteers were no longer willing to undergo the treatment. 4 means the volunteers felt better and breathed easier after the treatment. Be willing to undergo endoairway shock therapy again. |
Countries
China
Contacts
Primary ContactXin Jing, Dr
Backup ContactXing Qi Wang, Dr
Outcome results
None listed