Total Motile Sperm Count and Pregnancy Rate From Intrauterine Insemination

Effect of Post-Wash Total Motile Sperm Count on the Pregnancy Rate of Infertility Patients Undergoing Intrauterine Insemination

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05999591

Enrollment

330

Registered

2023-08-21

Start date

2022-11-30

Completion date

2023-01-22

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Insemination

Keywords

infertility, intrauterine insemination, post-wash total motile sperm count

Brief summary

Intrauterine insemination (IUI) is one of the most important infertility treatments. Infertility is failure to establish pregnancy (\>12 months) with regularly unprotected sexual intercourse. Post-wash total motile sperm count (TMSC) vaguely defined as a predictor of IUI pregnancy rate. The minimum value required is also not clear. This study aimed to further define the relationship and determine the minimum recommended value to achieve a satisfactory IUI pregnancy rate. Post-wash TMSC is predictive of IUI success. No optimal cut-off could be identified. In conclusion, post-wash TMSC is highly suggested as a quantitative predictor along with others in counseling and informed consent. The recommended threshold value is \>3 x 106.

Interventions

PROCEDUREIntrauterine insemination

Transfer of sperm into the fallopian tube through a specialised cannula

Study design

Observational model

COHORT

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

FEMALE

Healthy volunteers

Inclusion criteria

* post-wash total motile sperm count needed to be over 5 x 10\^5

Exclusion criteria

* missing data on pregnancy outcome and missing medical records

Design outcomes

Primary

Measure	Time frame	Description
Pregnancy rate	max 9 months	Pregnancy number divided by number of IUI cycles

Countries

Indonesia

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026