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The Cartilage and Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

The Effect of Ultrasonographic Cartilage Thickness and Quadriceps/Hamstring Muscle Thickness on Knee Pain in Patients With Rheumatoid Arthritis

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05999266
Enrollment
130
Registered
2023-08-21
Start date
2023-09-28
Completion date
2023-11-12
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cartilage Degeneration, Knee Pain Chronic, Muscle Loss, Rheumatoid Arthritis

Brief summary

The knee pain status of the patients who are followed in the rheumatology special branch of the Physical Medicine and Rehabilitation Outpatient Clinic and who meet the inclusion criteria will be questioned. In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest. The physician who performed the ultrasonographic measurements of the knee pain status of the patients does not know.

Interventions

In patients with or without knee pain, the cartilage thickness measurement of the knee joint will be measured from 3 points by ultrasound. At the same time, Quadriceps and Hamstring muscle thickness measurements of the patients will be made from the midpoints where the muscle thickness is the highest.

Sponsors

Sisli Hamidiye Etfal Training and Research Hospital
Lead SponsorOTHER

Study design

Observational model
CASE_ONLY
Time perspective
CROSS_SECTIONAL

Eligibility

Sex/Gender
FEMALE
Age
30 Years to 50 Years

Inclusion criteria

* Rheumatoid Arthritis \> Diagnosed for 1 year * -Female gender * -The patient has been in remission or low disease activity for at least 3 months * -Be able to ambulatory * -No significant deformity in the lower extremity joints

Exclusion criteria

* Patient with active arthritis or high disease activity * \- Significant deformity of the lower extremity joints and inability to ambulate * -Pregnant patient * \- Presence of malignancy * \- Patient with a severe psychiatric disorder and difficulty in cooperation * \- Presence of cardiovascular and pulmonary comorbidities that will prevent exercise * -Male gender

Design outcomes

Primary

MeasureTime frameDescription
Ultrasonographic Cartilage Thickness Measurementthrough study completion, an average of 1 monthTibial cartilage thickness will be visualized by ultrasound with the knee held in 30 degrees of flexion, and 3 measurements will be taken from the medial, lateral and midline.
Ultrasonographic Muscle Measurement Thickness Measurementthrough study completion, an average of 1 monthThe quadriceps muscle thickness will be measured by determining the midpoint between the SIAS and the patella while the patient is lying in the supine position. Hamstring muscle thickness will be measured at the intersection of a line drawn at 60% distal between the greater trochanter and the outer femoral condyle, and at the midline of the popliteal fossa, with the patient lying on the prone. These 2 measurements will be proportional to each other.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026