Aortic Dissection
Conditions
Keywords
aortic dissection, clinical characteristics, prognosis
Brief summary
This study will construct a retrospective-prospective long-term follow-up cohort and management system for aortic dissection through a multicentre collaborative network. This study aims to investigate the disease characteristics, progression patterns, clinical features, natural course and factors affecting the disease course and prognosis of patients with aortic dissection by retrospectively collecting data and prospectively enrolling patients.
Detailed description
This study aims to construct a retrospective-prospective long-term follow-up cohort and management system for aortic dissection through a multicentre collaborative network. The duration of the study will be divided into retrospective and prospective components. The retrospective study will collect cases of aortic dissection of different aetiologies from 2003-2022; the prospective study is expected to collect cases of aortic dissection from 2022-2030. The study is expected to assess the disease characteristics, progression patterns, clinical features, natural course and long-term prognosis of aortic coarctation.
Interventions
OTHERObservational
No interventions will be given to patients.
Sponsors
521 Hospital of NORINCO Group
Shaanxi Provincial People's Hospital
Xiangyang Central Hospital
Henan Provincial People's Hospital
First Affiliated Hospital Xi'an Jiaotong University
Study design
Observational model
COHORT
Time perspective
OTHER
Eligibility
Sex/Gender
ALL
Age
18 Years to 80 Years
Healthy volunteers
No
Inclusion criteria
* Age 18-80 years; * Meet diagnostic criteria for aortic dissection.
Exclusion criteria
* Age \<18 years or \>80 years; * Women who are pregnant and breastfeeding; * Patients and their families refuse or are unable to sign the informed consent form.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Change of post-operative survival rate | 3, 6, 9 month and 1, 2, 3, 4, 5 year after the surgery. | Post-operative survival rate of patients after aortic dissection surgery in 3, 6, 9 month and 1, 2, 3, 4, 5 year. The survival situation will be assessed by telephone follow-up. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Change of the incidence of MACCE | 3, 6, 9 month and 1, 2, 3, 4, 5 year after the surgery. | Major adverse cardio-cerebrovascular events included myocardial infarction, stroke, revascularization and all-cause death. The occurrence of MACCE will be assessed by telephone follow-up and medical records. |
| Incidence of any complications | 5 years after the surgery. | Any complications diagnosed by doctors. The occurrence of complications will be decided by medical records. |
Countries
China
Contacts
Primary ContactGuoliang Li
Backup ContactYang Yan
Outcome results
None listed