Application of New Magnetic Resonance UTE Technique in Hip Joint Lesions

Application of New Magnetic Resonance Technique-UTE in Hip Joint Lesions

Status

UNKNOWN

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05998720

Enrollment

150

Registered

2023-08-21

Start date

2023-07-01

Completion date

2024-06-13

Last updated

2023-08-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hip Disease

Brief summary

Explore the imaging and quantitative monitoring of hip bone, cartilage and ligament by magnetic resonance UTE technology, combined with QCT and DXA technology, to provide a more accurate basis for clinical evaluation and treatment.

Detailed description

Osteoporosis is a systemic bone metabolism-related disease characterized by decreased bone mass per unit volume, increased bone fragility, decreased bone density, thinning of the bone cortex and changes in bone microstructure. It often occurs in the lumbar spine and hip joint. Femoral neck fracture is a common complication of hip osteoporosis, which seriously affects people's quality of life. UTE technology can clearly image and quantify human cortical bone and cancellous bone, and advanced UTE technology such as STAIR-UTE and UTE-MT have made some progress in the field of osteoporosis. The purpose of this study was to explore UTE technology for imaging and quantitative study of cortical bone, cancellous bone and cartilage of hip joint, and to find more accurate imaging methods for clinical evaluation of hip osteoporosis and other diseases.

Interventions

None listed

Study design

Observational model

COHORT

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Healthy volunteers

Inclusion criteria

1. Patients with past or suspected osteoporosis and bone loss; 2. Patients with previous femoral neck fracture; 3. Patients with avascular necrosis of femoral head; 4. Hip osteoarthritis patients.

Exclusion criteria

1. Patients with metal implants in corresponding parts; 2. Claustrophobic.

Design outcomes

Primary

Measure	Time frame	Description
proton density fat fraction (PDFF)	Baseline (before surgery)	Magnetic resonance proton density fat fraction
T2 relaxation rate	Baseline (before surgery)	R2\*
Magnetization Transfer Ratio (MTR)	Baseline (before surgery)	magnetization transfer ratio
T1rho	Baseline (before surgery)	spin-lattice relaxation in the rotation ame

Secondary

Measure	Time frame	Description
Subjective rating values	Baseline (before surgery)	rating values

Countries

China

Contacts

Primary ContactXiaojun Chen

422175400@qq.com+8615820587112

Outcome results