Microscopic Colitis
Conditions
Brief summary
A pilot study investigating if orally administrated faecal microbiota transplantation capsules have the potential to treat active microscopic colitis.
Interventions
treatment with capsules
Sponsors
Hvidovre University Hospital
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
TREATMENT
Masking
NONE
Intervention model description
pilot trial
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
* Diagnosis of microscopic colitis * Date of diagnosis/histological confirmation \< 12 months * Active disease according to Hjortswang's criteria
Exclusion criteria
* Diagnosed with ulcerative colitis or Crohn's disease * Diagnosed with celiac disease * Active gastrointestinal infection * Previous bowel resection of bowel (except appendectomy) * Previous cholecystectomy * Treatment with systemic steroid within 4 weeks, including budesonide * Antibiotics 3 months prior * Severe immunodeficiency, * Pregnancy, planned pregnancy and breastfeeding * Treatment with constipants such as psyllium, loperamide, bile binders, opium drops or codeine up to 2 weeks before inclusion and during participation
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Treatment effect | 3 weeks | Proportion of participants in remission |
Outcome results
None listed