Multiple Myeloma
Conditions
Brief summary
Multiple myeloma (MM) is the most common bone marrow malignancy of terminally differentiated plasma cells. It accounts for about 1% of all malignant diseases and 10% of haematological malignancies and takes the second place after non-Hodgkin lymphoma . There are some serological and clinical criteria that help to detect the stage of MM and predict the patients' prognosis. These criteria include the level of M protein, calcium, haemoglobin, albumin, creatinine, β2-microglobulin and glomerular filtration rate (GFR).
Interventions
PROCEDUREBone marow biopsy and aspiration
Bone marrow biopsy and biopsy aspiration
DIAGNOSTIC_TESTbiochemical and heamatological tests
complete blood count ,serum urea and creatinine
Sponsors
Sohag University
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No
Inclusion criteria
1. Patients older than 18 year with newly diagnosed MM. 2. Approval to sign an informed written consent.
Exclusion criteria
* 1\. Patient younger than 18 years. 2.Refusal to sign an informed written consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Cycline D1 expression in bone marrow biopsy of multiple myeloma patient | 1 year | Cycline D1 expression in bone marrow biopsy of multiple myeloma patient |
Contacts
Primary ContactFainan K EL Kady, spcialist
Backup ContactDouaa M Sayed, professor
Outcome results
None listed