Periodic Fever Syndrome
Conditions
Keywords
PFAPA, periodic fever, homeopathy, Naranjo criteria
Brief summary
Periodic fever, aphthous stomatitis, pharyngitis, cervical adenitis (PFAPA) syndrome is frequently diagnosed in young children. Fevers recurring at a nearly predictable rate every three to eight weeks are the signature symptom of PFAPA syndrome. PFAPA is an acquired autoinflammatory disorder, which recurs in association with at least one sign of aphthous stomatitis, pharyngitis, and cervical lymph node enlargement. The aim of this retrospective case report is to gain an impression of the course of disease during individualized homeopathic treatment in children suffering from PFAPA.
Detailed description
In this retrospective study, the investigators collected the history and symptoms of 13 consecutive PFAPA patients. The investigators also described the individually chosen homeopathic medicinal products (HMPs) used, as well as the course of the disease. Clinical outcome of case reports was assessed using the Modified Naranjo Criteria for Homeopathy-Causal Attribution Inventory. Eight points are taken as the threshold for the possible correlation between homeopathic therapy and improvement of symptoms or cure in chronic cases
Interventions
Homeopathic globules were administered after careful anamnesis
Sponsors
Study design
Eligibility
Inclusion criteria
Children suffering from fever with at least one of the symptooms of PFAPA besides fever
Exclusion criteria
Parents not willing to sign informed consent.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Periodic fever flares | 30 months | Appearance of periodic fever flares |
Countries
Austria