Acne, Atopic Dermatitis, Chronic Hand Eczema, Hidradenitis Suppurativa, Palmoplantar Pustulosis, Plaque Psoriasis
Conditions
Brief summary
The purpose of the study is to collect different samples for molecular characterization of inflammatory skin diseases.
Detailed description
This study is being conducted to collect samples from subjects with various skin conditions as well as healthy volunteers. Collected samples may be used for different analyses including, but not limited to, biomarker and gene expression analyses.
Interventions
PROCEDUREBlood samples collection
biomarkers and optional genetic analysis
PROCEDUREOral samples collection
biomarkers analysis
PROCEDUREHair samples collection
biomarkers analysis
PROCEDURESkin samples collection (skin tape strip and/or skin biopsy, and/or skin scraping)
biomarkers analysis
PROCEDURESkin surface material samples
biomarkers analysis
PROCEDUREDrainage fluid samples collection
biomarkers analysis
PROCEDUREStool samples collection
biomarkers analysis
Sponsors
Innovaderm Research Inc.
Study design
Observational model
COHORT
Time perspective
CROSS_SECTIONAL
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
All subjects: 1. Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures. 2. Subject must be willing to comply with all study procedures and must be available for the duration of the study. Healthy volunteers: 3. Male or female subject aged 18 years or older, at the time of consent. 4. Subject is in good general health, according to the investigator's judgment. Subjects with Acne: 5. Male or female subject aged 18 to 45 years old, inclusive, at the time of consent. Subjects with AD: 6. Male or female subject aged 18 years or older, at the time of consent. 7. Subject has clinically confirmed diagnosis of active AD, according to Hanifin and Rajka criteria. Subjects with CHE: 8. Male or female subject aged 18 years or older, at the time of consent. 9. Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject). Subjects with HS: 10. Male or female subject aged 18 years or older, at the time of consent. 11. Subject has a clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before screening as determined by the investigator through subject interview and/or review of the medical history. Subjects with PPP: 12. Male or female subject aged 18 years or older at the time of consent. 13. Subject has at least a 6-month history of PPP as defined by the presence of pustules on palms and/or soles, but without evidence of infection on palms and soles (information obtained from medical chart or subject's physician, or directly from the subject). Subjects with psoriasis: 14. Male or female subject aged 18 years or older, at the time of consent.
Exclusion criteria
All subjects: 1. Subject is a female who is pregnant or who is planning to become pregnant during the study. 2. Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Untargeted biomarker approach with gene expression profile of skin samples | Day 1 |
| Exploratory biomarker and gene expression analyses. | Day 1 |
Countries
Canada
Contacts
CONTACTJulie Bedoucha, MSc
PRINCIPAL_INVESTIGATORRobert Bissonnette, MD
Innovaderm Research Inc.
Outcome results
None listed