Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals With Temporomandibular Dysfunction

Investigation of the Relationship Between Pain, Central Sensitization, Kinesiophobia and Stress Level in Individuals With Temporomandibular Dysfunction

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05993494

Enrollment

Registered

2023-08-15

Start date

2023-05-15

Completion date

2025-05-30

Last updated

2025-07-17

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain, Temporomandibular Joint Disorders

Keywords

Temporomandibular Joint Dysfunction, Pain, central sensitization, kinesiophobia, stress

Brief summary

Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Recent research has focused specifically on pain catastrophe, kinesiophobia, and central sensitization in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction.

Detailed description

Temporomandibular dysfunction (TMD) is a musculoskeletal and neuromuscular system-related condition that affects the masticatory muscles, temporomandibular joint, and other related structures. Psychological factors are stated as comorbid in individuals with TMD. Individuals with TMD-related pain show higher levels of stress, anxiety, depression, somatic awareness, pain catastrophizing, and kinesiophobia compared to controls. Therefore, recent research has focused on pain catastrophe, kinesiophobia, and central sensitization, especially in individuals with TMD. Therefore, the aim of this study is to examine the relationship between pain, central sensitization, kinesiophobia and stress level in individuals with temporomandibular dysfunction. Ninety patients aged 18-65 years, who have TME-related complaints for at least 3 months, and diagnosed with TMD as a result of clinical and radiological evaluation by a dentist will be included in the study.

Interventions

None listed

Study design

Observational model

CASE_ONLY

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 65 Years

Healthy volunteers

Inclusion criteria

* Between the ages of 18-65, * Having complaints related to TMJ for at least 3 months, * Patients diagnosed with TMD as a result of clinical and radiological evaluation by the dentist

Exclusion criteria

* Cognitive problems, * Any systemic joint or muscle disease (e.g. fibromyalgia, rheumatoid arthritis), * Serious systemic diseases, * Any neurological disorder (e.g. trigeminal neuralgia), * Pregnancy, breastfeeding status, * Previous treatment for TMJ or orofacial muscle pain

Design outcomes

Primary

Measure	Time frame	Description
Numeric Pain Scale	through study completion, an average of 1 year	Pain Assessment
Tampa Scale for Kinesiophobia	through study completion, an average of 1 year	Kinesiophobia Assessment for temporomandibular joint dysfunction
Perceived Stress Scale	through study completion, an average of 1 year	Stress Assessment
Central sensitization scale	through study completion, an average of 1 year	Central sensitization Assessment

Countries

Turkey (Türkiye)

Outcome results