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Treatment of Misophonia: Comparison of Exposure and Sound Therapy

Treatment of Misophonia: Comparison of Exposure and Sound Therapy

Status
Completed
Phases
NA
Study type
Interventional
Source
ClinicalTrials.gov
Registry ID
NCT05993286
Enrollment
76
Registered
2023-08-15
Start date
2019-03-01
Completion date
2021-04-01
Last updated
2023-08-15

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Misophonia

Keywords

Misophonia, sound therapy, exposure, psychoeducation, treatment

Brief summary

The goal of this clinical trial is to compare the effects of possible treatments in misophonics. The main question it aims to answer is: \- Is exposure more effective on misophonic symptoms than sound therapy? Participants are randomly assinged to three groups of treatment; 1. Psychoeducation 2. Psychoeducation + Exposure 3. Psychoeducation + Sound Therapy

Interventions

BEHAVIORALExposure Therapy

At Week 0, the homework was to expose oneself to these sounds for 20 minutes a day, three days a week for three weeks. At the Week 3 interview, the frequency and severity of the homework were adjusted based on the degree of improvement in the symptoms and the person's adherence to the instructions.

Participants were asked to listen to specifically modulated music for twenty minutes a day, three days a week, for the first three weeks. At the Week 3 assessment, if the patient reported no or little benefit in their misophonia symptoms, the instruction was modified (intensified) to listening to the same music for forty minutes a day, three days a week.

OTHERPsychoeducation

A psychoeducation session, prepared by the research team was delivered by the investigator to each patient at the study intake.

Sponsors

Hacettepe University
Lead SponsorOTHER

Study design

Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
TREATMENT
Masking
SINGLE (Subject)

Intervention model description

Participants were randomly assigned to one of three groups: psychoeducation only (the active control group), exposure therapy with psychoeducation, and sound therapy with psychoeducation. All participants were assessed at baseline, and then at 3rd and 6th weeks. All of them received psychoeducation at study intake. A random one third received no further active treatment, one third received exposure, and one third received sound therapy.

Eligibility

Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
No

Inclusion criteria

* People have Misophonia

Exclusion criteria

* Current psychosis * Mental retardation or dementia * those who had previously received exposure or sound therapy for misophonia symptoms.

Design outcomes

Primary

MeasureTime frameDescription
The mean change in Misophonia Total Score (MTS)Week 0 and Week 6The difference between MTS Week 0 and MTS Week 6 was calculated, divided by MTS Week 0, and multiplied by 100, to elicit the percent change in MTS between Week 0 and Week 6.
The improvementWeek 3 and Week 6It was rated by the investigator (KBA) based on her clinical judgement (0=some worsening, 1=no improvement, 2=some improvement, 3=moderate improvement, 4=much improvement). If there was a moderate to much improvement at any point, the case was rated as improved; and not improved if the score was little worsening, no improvement, or some improvement.

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026