Magnetic Resonance Imaging
Conditions
Brief summary
The goal of the current project is to explore and develop the technical feasibility of non-invasive imaging of the human musculoskeletal system and head with the first 7T MR scanner with a CE mark to identify areas where the higher field promises significant benefits in qualitative image quality. For a subset of the planned exams, state-of-the art 7T or 3T images will be used as standard of reference to comparatively gauge the qualitative image quality of the investigational 7T images.
Interventions
OTHER7 T MRI vs 3 T MRI
Adult healthy and patient volunteers will undergo a ca. 1 hour examination of non-invasive magnetic-resonance imaging at 7T, and, if appropriate, a closely matching examination at 3T as a standard of reference.
Sponsors
Reto Sutter, MD
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Consent to undergo a 7T (and, if appropriate a comparative 3T) MRI exam. * For some of the consistent small series: presence of a specific condition of the musculoskeletal system or of the head. This can include traumatic or degenerative changes, e.g., of tendons, cartilage, muscle, peripheral nerves, ligaments, and bones, or in the brain, as well as focal lesions, e.g., tumors.
Exclusion criteria
* Contraindications to undergo a MRI examination at a field strength of 7 Tesla or at 3 Tesla. * Irregular anatomy and/or tissue properties * Inability to consent - for any reason. * Body mass above 200 kg. * Body mass below 30 kg. * Women: pregnancy. * Age below 18. * Known or suspected non-compliance, drug or alcohol abuse. * Inability to follow the procedures of the study.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Qualitative image quality of 7 T MRI | through study completion, an average of 1 year | Current-day feasibility of various types of MR examinations of the human musculoskeletal system. The primary outcomes of small consistent series of the study are visual gradings and qualitative measures of image quality. Image quality is rated by independent readers using Likert scales. |
Countries
Switzerland
Contacts
Primary ContactReto Sutter, Prof.
Backup ContactDaniel Nanz, Prof.
Outcome results
None listed