Examining Racial and Socioeconomic Differences in Chronic Low Back Pain

Racial and Socioeconomic Differences in Chronic Low Back Pain

Status

Recruiting

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05991440

Acronym

ERASED

Enrollment

240

Registered

2023-08-14

Start date

2024-04-22

Completion date

2028-12-31

Last updated

2026-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Chronic Pain

Keywords

lower back pain, Race, Socioeconomic

Brief summary

The purpose of this research study is to gain a better understanding of how people's racial background and socioeconomic status (e.g., income, education, and employment) impact their experiences of chronic low back pain (cLBP).

Interventions

None listed

Study design

Observational model

CASE_CONTROL

Time perspective

PROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

18 Years to 85 Years

Healthy volunteers

Inclusion criteria

Inclusion: * Non-specific cLBP that has persisted for at least 3 months and has resulted in pain on at least half the days in the past 6 months. * Age 18 - 85; the lower end of this age range was chosen to capture the growing prevalence of young adults with cLBP, and participants over 85 years are increasingly likely to meet one or more

Exclusion criteria

. * Participants report ethnic group as non-Hispanic and racial group as either Black/African American or White/Caucasian. Exclusion: * Low back pain that is attributable to other factors such as ankylosing spondylitis, infection, malignancy, compression fracture of other trauma. * Systemic rheumatic disease/condition (e.g. rheumatoid arthritis, systemic lupus erythematosus, fibromyalgia). * Any other chronic pain condition that the participant believes to be more prominent or severe than the low back pain. * A history of clinically significant surgery to the low back within the past year. * Uncontrolled hypertension (i.e. SBP/DBP of \> 150/95), cardiovascular or peripheral arterial disease. * Poorly controlled diabetes (HbA1c \> 8%). * Neurological disease (e.g. Parkinson's, multiple sclerosis, epilepsy). * Serious psychiatric disorder requiring hospitalization within the past 12 months or characterized by active suicidal ideation. * Diminished cognitive function that would interfere with understanding of study procedures.

Design outcomes

Primary

Measure	Time frame	Description
To elucidate racial group disparities in clinical symptoms among NHBs and NHWs with cLBP.	two years	Clinical pain severity will be observed through quantitative sensory testing and self-reported questionnaires and surveys.
To elucidate racial group disparities in experimental pain sensitivity among NHBs and NHWs with cLBP.	two years	Quantitative sensory testing equipment and biological markers assayed via blood samples.
To elucidate racial group disparities in psychosocial risk factors, among NHBs and NHWs with cLBP.	two years	Psychosocial risk factors that will be observed will be greater increases in depressive symptoms, anxiety, and perceived stress, as well as greater social isolation and loneliness through the use of self-reported questionnaires and surveys.

Countries

United States

Contacts

CONTACTBurel R Goodin, PhD

burel@wustl.edu314-273-6403

PRINCIPAL_INVESTIGATORBurel Goodin, PhD

Washington University School of Medicine

Outcome results