Surgical Site Infection, Surgical Wound, Surgical Incision, Emergency Laparotomies, Laparotomies, Post Operative Wound Infection, Wound Infection, Seroma
Conditions
Brief summary
The goal of this clinical trial is to compare the outcomes of High-volume saline irrigation vs Povidone-iodine solution cleaning of the intraoperative incision wound in preventing superficial surgical site infections in patients undergoing emergency laparotomies. The main question it aims to answer are: * Incidence of SSI after intervention * Length of hospital stay Participants will be randomly assigned to two groups receiving either of the two groups: Group A: 1000ml of IOWI with saline solution prior to incision closure Group B: The incisional wound will be closed conventionally without irrigation. Researchers will compare groups A( experimental group) and B (control group) to compare the incidence of superficial surgical site infections after intervention.
Interventions
PROCEDURE0.9% saline solution
During emergency laparotomy, after the primary surgical procedure. the sheath will be sutured and the incision site will then be irrigated with three rounds of 1 liter of 0.9% saline solution, which will be completely aspirated before the closure of the incisional wound in experimental group.
PROCEDUREPovidone-iodine Swab
No intra-operative wound lavage done, and wound would be cleaned with povidone doused swab.
Sponsors
Dow University of Health Sciences
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
TRIPLE (Subject, Caregiver, Outcomes Assessor)
Eligibility
Sex/Gender
ALL
Age
18 Years to 60 Years
Healthy volunteers
No
Inclusion criteria
* • Patients undergoing emergency laparotomy under the care of surgical-6 unit of Dr. Ruth K. M. Pfau Civil Hospital Karachi * The age of patients should be between 18-60 years old.
Exclusion criteria
* Diabetic patients * Immune-suppressed patients * Patients taking steroids * Patients undergoing chemo-radiotherapy. * Pregnant females * Previous abdominal surgery within the last 30 days. * Presence of concurrent abdominal wall infections. * Trauma Laparotomies * Large Bowel perforations
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Incidence of Superficial Surgical site infections | Upto 4 weeks post-operatively | Development of Superficial Surgical Site Infection as determined by the CDC guidelines. |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| Length of Hospital Stay | Upto 4 weeks post-operatively | Number of in-hospital days (from time of admission to time of discharge) |
Countries
Pakistan
Contacts
Primary ContactOmer Bin Khalid, Assist Prof.
Backup ContactAfeera Ahmed, Undergraduate
Outcome results
None listed