Skin Condition
Conditions
Brief summary
To assess melon and oil olive pressed candy on skin condition improvement
Interventions
DIETARY_SUPPLEMENTPlacebo candy
consume 2 tablets per day
DIETARY_SUPPLEMENTmelon and oil olive pressed candy
consume 2 tablets per day
Sponsors
TCI Co., Ltd.
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
OTHER
Masking
DOUBLE (Subject, Investigator)
Eligibility
Sex/Gender
ALL
Age
18 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Healthy adults aged above 18 years old * ITA° value 20°-41°
Exclusion criteria
* Involuntary subjects. * Subjects who have a history of skin diseases such as psoriasis, eczema, atopic dermatitis, severe acne; or suffer from other chronic systemic disease. * Those with known cosmetic, drug or food allergies. * Female who is pregnant or nursing or planning to become pregnant during the course of the study. * Subjects who have taken oral or topical corticosteroids and other anti-inflammatory drugs in the past 1 month. * Use of any products or drugs that affect skin color such as fruit acid, salicylic acid (such as Hydroquinone preparations) in the past 2 months. * In the past 3 months, the test site has used retinoic acid preparations or undergone chemical peeling, laser, pulse light and other medical aesthetic therapists * Subjects who can not avoid long-term sun exposure
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| The change of skin brown spots | Change from Baseline skin brown spots at 12 weeks | VISIA Complexion Analysis System was utilized to measure skin brown spots. Units: arbitrary units |
| The change of skin b* value | Change from Baseline b* value at 12 weeks | Chroma Meter MM500 was utilized to measure skin b\* value. Units: arbitrary units |
| The change of skin ITA° value | Change from Baseline ITA° value at 12 weeks | Chroma Meter MM500 was utilized to measure skin ITA° value. Units: arbitrary units |
| The change of skin spots | Change from Baseline skin spots at 12 weeks | VISIA Complexion Analysis System was utilized to measure skin spots. Units: arbitrary units |
| The change of skin UV spots | Change from Baseline skin UV spots at 12 weeks | VISIA Complexion Analysis System was utilized to measure skin UV spots. Units: arbitrary units |
| The change of skin wrinkles | Change from Baseline skin wrinkles at 12 weeks | VISIA Complexion Analysis System was utilized to measure skin wrinkles. Units: arbitrary units |
| The change of skin texture | Change from Baseline skin texture at 12 weeks | VISIA Complexion Analysis System was utilized to measure skin texture. Units: arbitrary units |
| The change of skin melanin index | Change from Baseline skin melanin index at 12 weeks | Mexameter® MX18 was utilized to measure skin melanin index. Units: arbitrary units |
| The change of skin erythema index | Change from Baseline skin erythema index at 12 weeks | Mexameter® MX18 was utilized to measure skin erythema index. Units: arbitrary units |
| The change of skin L* value | Change from Baseline L* value at 12 weeks | Chroma Meter MM500 was utilized to measure skin L\* value. Units: arbitrary units |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| The change of TEAC of blood | Change from Baseline TEAC at 12 weeks | Venous blood was sampled to measure TEAC |
| The change of SOD of blood | Change from Baseline SOD at 12 weeks | Venous blood was sampled to measure SOD |
| The change of GSH-Px of blood | Change from Baseline GSH-Px at 12 weeks | Venous blood was sampled to measure GSH-Px |
Other
| Measure | Time frame | Description |
|---|---|---|
| The change of self-assessment skin and hair condition | Change from Baseline skin and hair condition at 12 weeks | A self-assessment questionnaire was collected to evaluate skin and hair condition |
Countries
Taiwan
Outcome results
None listed