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Effect of Aerobic Exercise in Patients With Essential Hypertension

Effects of Supervised Versus Unsupervised Aerobic Exercise Training on Weight Loss, Functional Capacity, Quality of Life and Depression Level in Patients With Essential Hypertension

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05987436
Enrollment
138
Registered
2023-08-14
Start date
2017-11-01
Completion date
2019-12-01
Last updated
2023-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aerobic Exercise, Essential Hypertension

Keywords

supervised aerobic exercise, functional capacity, quality of life, depression level, essential hypertension

Brief summary

The goal of this observational study is to evaluate the effects of a supervised aerobic exercise training program on weight loss, functional capacity, quality of life (QoL), and depression levels in patients with essential hypertension.

Detailed description

Patients who chose the treatment type according to personal preferences were divided into two groups: Group 1(n:91) exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory, and group 2(n:47) was advised to maintain dietary habits and physical activity levels. Body weight, serum lipid levels, functional capacity, QoL, and depression level of all the participants were evaluated at baseline and 6 weeks later.

Interventions

Group 1 exercised for six weeks, five sessions per week under the supervision of a medical doctor in the aerobic exercise laboratory.

Sponsors

TC Erciyes University
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
PROSPECTIVE

Eligibility

Sex/Gender
ALL
Age
18 Years to 75 Years
Healthy volunteers
Yes

Inclusion criteria

* Over 18 years of age, * Absence of concomitant other metabolic and cardiovascular diseases.

Exclusion criteria

* Having suffered an event of ischaemic heart disease (\<6 months), * Secondary hypertension, * Hypertrophic obstructive cardiomyopathy, * Congestive heart failure, * Uncontrolled cardiac arrhythmia, * Thyroid dysfunction, * Diabetes mellitus, * Symptomatic peripheral arterial occlusive disease, * Aortic insufficiency or stenosis, * Pulmonary or heart disease with dyspnoea at small or moderate effort, * An outbreak of orthopedic problems on hip, knee or ankles, such as arthroplasty, contracture or severe osteoarthritis, * Using of antidepressant or anxiolytic drugs, * Pregnancy, * Cognitive disfunction.

Design outcomes

Primary

MeasureTime frameDescription
Body weightwas measured at the pre-treatment period and the post-treatment 6th week for all the participants by the same physician.kilograms
Blood samplesTwelve-hour fasting blood samples were collected between 6.00 am, and 10.00 am at baseline and week 6.Serum total cholesterol, high-density lipoprotein (HDL) cholesterol, low-density lipoprotein (LDL) cholesterol, very-low-density lipoprotein (VLDL) cholesterol, and triglycerides
The functional capacity6MWT was assessed in face-to-face interviews before and immediately after the treatment was completed.The 6MWT test and the estimated metabolic equivalents or METs were used performed to evaluate functional capacity.
Quality of LifeSF36 was assessed in face-to-face interviews before and immediately after the treatment was completed.Quality of life was assessed with Short Form-36 (SF-36).
Depression levelBDI was assessed in face-to-face interviews before and immediately after the treatment was completed.Depression level was assessed Beck Depression Inventory (BDI).

Countries

Turkey (Türkiye)

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026