Assessment of Long-term Effects of Tachosil

Assessment of Long-term Effects of Intraoperative Use of a Carrier-bound Fibrin Sealant (TachoSil®). We Had to Continue to Use it?

Status

Completed

Phases

Unknown

Study type

Observational

Source

ClinicalTrials.gov

Registry ID

NCT05986201

Enrollment

Registered

2023-08-14

Start date

2016-02-01

Completion date

2023-06-01

Last updated

2023-08-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Fibrin Sealant, Haemostasis

Brief summary

This study aimed to analyse the long-term effects of a carrier-bound fibrin sealant (CBFS) after abdominal surgery by following up patients years after application.

Interventions

DEVICETachoSil®

TachoSil®, a carrier-bound fibrin sealant (CBFS), is a haemostatic tissue sealant composed of a collagen sponge, made from horse tendons, coated on one side with dried human fibrinogen and human thrombin.

Study design

Observational model

CASE_CONTROL

Time perspective

RETROSPECTIVE

Eligibility

Sex/Gender

ALL

Age

32 Years to 87 Years

Inclusion criteria

* type of surgery, indication for surgery, type of disease

Exclusion criteria

* dead patients, not available on call.

Design outcomes

Primary

Measure	Time frame	Description
fibrotic reaction	10 years	The evaluation focused on individuation of the area treated with CBFS, comprehensive analysis of the dimensions of the area treated if visible, and evolution, focusing on the presence of fibrosis, sclerosis, collections, cysts, or pseudocysts. The formation of a fibrotic reaction was related to the presence of residual tissue on CT during follow-up.

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026