Sarcopenia
Conditions
Brief summary
Studies conducted so far added the dietary supplements along with resistance training as an intervention, we could not determine whether the observed effects of the intervention were due to the training program and/or dietary supplements.
Detailed description
This study will investigate the effects of high intensity resistance training solely in the possible sarcopenia cases which has not done before, to author's knowledge. Furthermore this study will help clinicians to individualize and optimize the therapy for specific patient subgroups, improve the potential of this therapy to improve human function and well being, facilitate timely interventions in community healthcare and prevention settings, which will contribute to higher awareness of sarcopenia prevention and interventions in diverse health care settings.
Interventions
High intensity resistance training will be performed 3 times a day for sixteen weeks
Sponsors
Riphah International University
Study design
Allocation
RANDOMIZED
Intervention model
PARALLEL
Primary purpose
PREVENTION
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
60 Years to No maximum
Healthy volunteers
Yes
Inclusion criteria
* Both male and female * Age more than 60 years * Possible sarcopenia cases as defined by Asian Working Group for Sarcopenia (Handgrip strength: Male less than 26kg and Female less than 18kg, 5 time chair stand test more than/equals to 12 seconds)
Exclusion criteria
* Orthopedic surgery in last one year * Neurological disorders like stroke etc * History of recent fractures * Metabolic disorders like DM etc * Actively involved in exercise programs * Cognitive impairment that could confound the assessment * Wheelchair or bed bound individuals
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| Hand Dynamometer | 16 weeks | it used to measure the hand grip strength. the test-retest reliability is 0.91 and 0.95 with excellent reliability. The assessment will be made at baseline, week 8 and 16 |
| Short performance physical battery | 16 Week | an objective assessment tool for evaluating lower extremity functioning in older persons. the test-retest reliability is 0.87. It was used to measure at baseline, week 8 and 16 |
Secondary
| Measure | Time frame | Description |
|---|---|---|
| FRAIL | 16 week | The questionnaire aims at fatigue, resistance, ambulation, illness and loss of weight. It is a self reported questionnaire. The sensitivity of FRAIL is 85.8% and a specificity of 80.6%. The test will be measured at baseline, week 8 and 16 |
Countries
Pakistan
Outcome results
None listed