Insomnia Disorder
Conditions
Brief summary
Based on real world and focusing on patients with chronic sleep disorders, this study conducts a data-driven subtyping research on the clinical symptoms, polysomnography, near-infrared scanning, molecular genetics, and other characteristics of chronic insomnia disorders. It constructs a multimodal therapeutic outcome prediction model, providing a basis for personalized interventions for chronic insomnia disorder.
Interventions
BEHAVIORALCognitive Behavioral Therapy for Insomnia
Cognitive Behavioral Therapy for Insomnia is the main therapy for the patients. Medications include sedative-hypnotics and antidepressants with a sedative effect.
Sponsors
Shanghai Mental Health Center
Study design
Allocation
NA
Intervention model
SINGLE_GROUP
Primary purpose
DIAGNOSTIC
Masking
NONE
Eligibility
Sex/Gender
ALL
Age
18 Years to 65 Years
Healthy volunteers
No
Inclusion criteria
1. Aged between 18 and 65 years, regardless of gender; 2. Currently meeting the diagnostic criteria for insomnia disorder according to the Fifth Edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM-5); 3. Pittsburgh Sleep Quality Index (PSQI) total score ≥ 10; 4. Sufficient level of education and comprehension to complete the required examinations and assessments for this study; 5. Voluntarily participating in this research and signing the informed consent form.
Exclusion criteria
1. Currently diagnosed with other sleep disorders (sleep-related breathing disorders, periodic limb movement disorder, parasomnias, central disorders of hypersomnolence, circadian rhythm sleep-wake disorders, etc.); 2. Currently diagnosed with organic brain diseases (epilepsy, cerebrovascular disease, etc.) or other organic diseases; 3. Patients with a history of or currently diagnosed with bipolar and related disorders, obsessive-compulsive and related disorders, schizophrenia spectrum and other psychotic disorders, trauma and stressor-related disorders, dissociative disorders, or eating disorders; 4. Women who are pregnant, breastfeeding, or planning to become pregnant during the study period; 5. Insomnia caused by alcohol or substance abuse; 6. High suicide risk, with HAMD-17 suicide factor score \> 2; 7. Inability to cooperate with near-infrared examinations and polysomnography due to physical conditions such as head injury, etc.
Design outcomes
Primary
| Measure | Time frame | Description |
|---|---|---|
| polysomnography | the end of the eighth week | change in total sleep time recorded by polysomnography |
| PSQI | the end of the 24th, 36th, 48th week | change in total sleep time according to PSQI scale |
Countries
China
Contacts
Primary ContactDongbin LYU
Outcome results
None listed