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Outcomes After Visceral Aortic Coral Reef Surgery

Long Term Outcomes After Visceral Aortic Endarteriectomy for Coral Reef Lesion

Status
Completed
Phases
Unknown
Study type
Observational
Source
ClinicalTrials.gov
Registry ID
NCT05983510
Enrollment
40
Registered
2023-08-09
Start date
2018-01-01
Completion date
2023-07-01
Last updated
2023-08-09

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Aortic Coral Reef

Brief summary

Coral reef aorta is defined by a calcified stenosis of the visceral aorta which can cause leg claudication, renal failure and visceral ischemia depending the type and localisation of the stenosis. This pathology is rare and is usually treated by open surgery with aortic endarteriectomy. Little is know about the outcomes after such aggressive surgery with short series and short follow up. The authors propose a retrospective study from their institution to explore the post operative and long term outcomes after this surgery.

Detailed description

Coral reef aorta is defined by a calcified stenosis of the visceral aorta which can cause leg claudication, renal failure and visceral ischemia depending the type and localisation of the stenosis. This pathology is rare and is usually treated by open surgery with aortic endarteriectomy. Little is known in the literature regarding the outcomes of this aggressive surgery. The authors propose a retrospective study from their institution describing the type of surgery realised. They describe the post operative outcomes of this surgery in term of cardiologic, respiratory, renal complication a,d surgical complication. Moreover they follow the patients to present long term outcomes of this pathology with a description of the post operative recurrence of a coral reef, the permeability of the different target vessel and the cardiologic, respiratory and renal evolution of the different patients.

Interventions

PROCEDUREAortic endarteriectomy

Thoraco-phreno-lumbotomy with thoracic aortic cross clamping Longitudinal aortotomy Endarteriectomy of the aorta Direct closure more or less bypass to the visceral arteries and downstream aorta reconstruction.

Sponsors

University Paul Sabatier of Toulouse
Lead SponsorOTHER

Study design

Observational model
COHORT
Time perspective
RETROSPECTIVE

Eligibility

Sex/Gender
ALL
Healthy volunteers
No

Inclusion criteria

* Coral reef surgery * Urgent intervention * Claudication, renal, visceral involvement * Thoracic aortic cross clamping (above coeliac trunk)

Exclusion criteria

* simple visceral aorto thrombectomy without opening laterally the aorta * Pregnant

Design outcomes

Primary

MeasureTime frameDescription
Reintervention1 month after surgeryNeed of reintervention before discharge
Major adverse cardiac event (MACE)1 month after surgeryPost operative cardiologic complication

Secondary

MeasureTime frameDescription
Long term follow up1 month, 1 year, yearly up to 5 yearsCumulative survival rate
Target vessel patency1 month, 1 year, yearly up to 5 yearsPermeability of the different vessel (renal and visceral arteries) on CT scan or Duplex ultrasound
Kidney function evolution1 month, 1 year, yearly up to 5 yearsglomerular filtration rate evolution,

Countries

France

Outcome results

None listed

Source: ClinicalTrials.gov · Data processed: Feb 4, 2026